ArticleScientific reports2022
Utility of standard diffusion-weighted magnetic resonance imaging for the identification of ischemic optic neuropathy in giant cell arteritis.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Utility of Diffusion-weighted Magnetic Resonance Imaging in Differentiating Connective Tissue Disease–associated Optic Neuritis from Idiopathic Optic NeuritisCurrent medical imaging · 2026Observational
- The diagnostic performance of ss-EPI-DWI, rs-EPI-DWI (RESOLVE) and TGSE-BLADE-DWI in a model of retinal ischemia: a comparative phantom study.Scientific reports · 2025Article
- Diffusion weighted imaging-based differentiation of arteritic and non-arteritic anterior ischemic optic neuropathy.BMC medical imaging · 2025Article
- Optic nerve sheath measurement to monitor disease activity in giant cell arteritis: a pilot study.Clinical rheumatology · 2024Article
- DWI scrolling artery sign for the diagnosis of giant cell arteritis: a pattern recognition approach.RMD open · 2024Article
- Perioperative Blindness in Spine Surgery: A Scoping Literature Review.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study assessed diffusion abnormalities of the optic nerve (ON) in giant cell arteritis (GCA) patients with acute onset of visual impairment (VI) using diffusion-weighted magnetic resonance imaging (DWI). DWI scans of GCA patients with acute VI were evaluated in a case-control study. Two blinded neuroradiologists assessed randomized DWI scans of GCA and controls for ON restricted diffusion. Statistical quality criteria and inter-rater reliability (IRR) were calculated. DWI findings were compared to ophthalmological assessments. 35 GCA patients (76.2 ± 6.4 years; 37 scans) and 35 controls (75.7 ± 7.6 years; 38 scans) were included. ON restricted diffusion was detected in 81.1% (Reader 1) of GCA scans. Localization of ON restricted diffusion was at the optic nerve head in 80.6%, intraorbital in 11.1% and affecting both segments in 8.3%. DWI discerned affected from unaffected ON with a sensitivity, specificity, positive and negative predictive value of 87%/99%/96%/96%. IRR for ON restricted diffusion was κ
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