Evidence map›Paper›PMID 36192131›Full record

ArticleRNA (New York, N.Y.)2022

HITS-CLIP analysis of human ALKBH8 reveals interactions with fully processed substrate tRNAs and with specific noncoding RNAs.

Ivana Cavallin, Marek Bartosovic, Tomas Skalicky, Praveenkumar Rengaraj, Martin Demko, Martina Christina Schmidt-Dengler, Aleksej Drino, Mark Helm, Stepanka Vanacova

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. tRNA modification enzyme-dependent redox homeostasis regulates synapse formation and memory.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Ivana CavallinCentral European Institute of Technology, Masaryk University, 625 00 Brno, Czech Republic.
Marek BartosovicCentral European Institute of Technology, Masaryk University, 625 00 Brno, Czech Republic.ORCID 0000-0003-2057-6050
Tomas SkalickyCentral European Institute of Technology, Masaryk University, 625 00 Brno, Czech Republic.ORCID 0000-0002-1976-3636
Praveenkumar RengarajCentral European Institute of Technology, Masaryk University, 625 00 Brno, Czech Republic.
Martin DemkoCentral European Institute of Technology, Masaryk University, 625 00 Brno, Czech Republic.
Martina Christina Schmidt-DenglerJohannes Gutenberg-Universität Mainz, Institute of Pharmaceutical and Biomedical Science (IPBS), D-55128 Mainz, Germany.ORCID 0000-0003-3075-0630
Aleksej DrinoMedical University of Vienna, Center for Anatomy and Cell Biology, 1090 Vienna, Austria.ORCID 0000-0003-0134-8335
Mark HelmJohannes Gutenberg-Universität Mainz, Institute of Pharmaceutical and Biomedical Science (IPBS), D-55128 Mainz, Germany.ORCID 0000-0002-0154-0928
Stepanka VanacovaCentral European Institute of Technology, Masaryk University, 625 00 Brno, Czech Republic.ORCID 0000-0001-8807-0684
Central European Institute of Technology · CZJohannes Gutenberg University Mainz · DEMedical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transfer RNAs acquire a large plethora of chemical modifications. Among those, modifications of the anticodon loop play important roles in translational fidelity and tRNA stability. Four human wobble U-containing tRNAs obtain 5-methoxycarbonylmethyluridine (mcm

Indexed as

Chromatin Immunoprecipitation SequencingRNA, TransferAlkB Homolog 8, tRNA MethyltransferaseAnticodonHumansRNA, UntranslatedALKBH8 protein, humanAlkB Homolog 8, tRNA MethyltransferaseAnticodonRNA, TransferRNA, UntranslatedALKBH8HITS-CLIPmcm5s2Umcm5UTrm9wobble uridine modification

Identifiers

PMID36192131
PMCPMC9670814
OpenAlexW4300861904

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.