Evidence map›Paper›PMID 36191873›Full record

Observational studyThe American journal of tropical medicine and hygiene2022

Measles Vaccination Immunogenicity and Association with Caste in Chandigarh, India.

Abram L Wagner, Joseph L Mathew, Bradley F Carlson, Aparna G Kachoria, Bhavneet Bharti, Vanita Suri, Matthew L Boulton

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in The American journal of tropical medicine and hygiene, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Abram L WagnerDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Joseph L MathewAdvanced Pediatrics Center, PGIMER, Chandigarh, India.
Bradley F CarlsonDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Aparna G KachoriaDepartment of Maternal and Child Health, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina.
Bhavneet BhartiAdvanced Pediatrics Center, PGIMER, Chandigarh, India.
Vanita SuriDepartment of Obstetrics & Gynecology, PGIMER Chandigarh, India.
Matthew L BoultonDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Post Graduate Institute of Medical Education and Research · INUniversity of Michigan–Ann Arbor · USUniversity of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measles affects those of lower socioeconomic status disproportionately. This study evaluated the impact of measles vaccination on antibody titers 3 months after vaccination across different socioeconomic groups, with a focus on caste. In total, 169 infants in Chandigarh, India, had serum samples collected immediately prior to vaccination at 9 months of age and 3 months later. Overall, 126 infants (76%) were seropositive (antibody titers > 12 mIU/mL), 26 (16%) were borderline (8-12 mIU/mL), and 14 (8%) were seronegative (< 8 mIU/mL). Seropositivity (versus borderline/seronegative infants) was 0.78 times as high among individuals from the historically marginalized scheduled castes/scheduled tribes compared with the others caste grouping (95% CI, 0.62-0.98). Antibody response was not tied to anthropometric measures but was attenuated among scheduled castes/scheduled tribes with higher incomes. This study provides observational evidence that social structures can be associated with individual immune responses.

Indexed as

Antibodies, ViralMeaslesHumansIndiaInfantMeasles VaccineSocial ClassVaccinationAntibodies, ViralMeasles Vaccine

Identifiers

PMID36191873
PMCPMC9709014
OpenAlexW4300863006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.