Evidence map›Paper›PMID 36191258›Full record

ArticleAmerican journal of respiratory and critical care medicine2023

Obstructive Sleep Apnea-induced Endothelial Dysfunction Is Mediated by miR-210.

Fenqing Shang, Shen-Chih Wang, Brendoan Gongol, So Yun Han, Yoshitake Cho, Cara R Schiavon, Lili Chen, Yuanming Xing, Yingshuai Zhao, Ming'an Ning and 11 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Sleep, Neural Circulatory Control, and Cardiovascular Disease: A Mechanistic Review.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  4. Mechanisms Linking Sleep-Disordered Breathing and Cardiometabolic Disease Risk.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Obstructive Sleep Apnea Endophenotypes.Sleep science (Sao Paulo, Brazil) · 2025
    Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 8 institutions in 3 countries.

Fenqing ShangTranslational Medicine Centre, Xi'an Chest Hospital, and.
Shen-Chih WangDepartment of Anesthesiology.
Brendoan GongolDivision of Cardiology and.
So Yun HanDivision of Cardiology and.
Yoshitake ChoDivision of Cardiology and.
Cara R SchiavonWaitt Advanced Biophotonics Center, Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California.
Lili ChenCardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yuanming XingCardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yingshuai ZhaoDepartment of General Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, China.
Ming'an NingDepartment of Cardiology, Xi'an No. 1 Hospital, Xi'an, China; and.
Xuan GuoDepartment of Cardiology, Xi'an No. 1 Hospital, Xi'an, China; and.
Fangzhou HeCardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Yuyang LeiCardiovascular Research Center, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Liuyi WangDepartment of General Medicine, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, China.
Uri ManorWaitt Advanced Biophotonics Center, Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California.
Traci MarinDivision of Cardiology and.
Kun-Ta ChouCenter of Sleep Medicine, and.ORCID 0000-0002-4822-5474
Ming HeDivision of Cardiology and.
Po-Hsun HuangDepartment of Critical Care Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
John Y-J ShyyDivision of Cardiology and.ORCID 0000-0002-5625-753X
Atul MalhotraDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Diego, La Jolla, California.
Xi'an Jiaotong University · CNSalk Institute for Biological Studies · USZhengzhou University · CNNational Yang Ming Chiao Tung University · TWSleepMed · USUniversity of California San Diego · USVictor Valley College · USXi'an Chest Hospital · CN

Funding

Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Ye Zheng · 1985 to 2026
$82.8M
Shear Regulation of MicroRNA Transportomes and Targetomes in Vascular HomeostasisR01HL106579 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHIEN, SHU, SHYY, JOHN YJ · 2011 to 2022
$8.3M
Is Obstructive Sleep Apnea Important in the Development of Alzheimer's DiseaseR01AG063925 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2020 to 2024
$3.7M
Underlying mechanisms of obesity-induced obstructive sleep apneaR01HL148436 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Atul Malhotra · 2020 to 2026
$3.4M
Sleep Apnea Endophenotypes: One Size Does Not Fit AllR01HL154926 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2021 to 2025
$3.3M
VentNet: A Real-Time Multimodal Data Integration Model for Prediction of Respiratory Failure in Patients with COVID-19R01HL157985 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, NEMATI, SHAMIM · 2022 to 2025
$2.9M
Training in the Next Generation in Respiratory ScienceT32HL134632 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, POWELL, FRANK L. · 2017 to 2021
$2.1M
Training in Bioengineering Research and Technology Development in Cardiovascular in Cardiopulmonary Health and DiseaseT32HL160507 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Karen L Christman, Andrew D. McCulloch · 2022 to 2026
$1.6M
A Novel Model System for Restoring Hearing in vivoR21DC018237 · NIDCD · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI COLEMAN, TODD P, KYRIAKAKIS, PHILLIP · 2020 to 2021
$505k
Actin-mediated regulation of organelle dynamics in Charcot-Marie-Tooth diseaseF32GM137580 · NIGMS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI SCHIAVON, CARA RAE · 2021 to 2022
$136k
NCI NIH HHS P30 CA014195NHLBI NIH HHS R01 HL106579NHLBI NIH HHS R01 HL148436NHLBI NIH HHS R01 HL154926NHLBI NIH HHS R01 HL157985NHLBI NIH HHS T32 HL134632NHLBI NIH HHS T32 HL160507NIA NIH HHS R01 AG063925NIDCD NIH HHS R21 DC018237NIGMS NIH HHS F32 GM137580NIH HHS F32GM137580NIH HHS R01HL106579NIH HHS R01HL148436
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardiovascular DiseasesMicroRNAsSleep Apnea, ObstructiveVascular DiseasesAnimalsHumansHypoxiaMiceMicroRNAsMIRN210 microRNA, humanMIRN210 microRNA, mouseendotheliummiR-210mitochondrial dysfunctionobstructive sleep apnea

Identifiers

PMID36191258
PMCPMC9896631
OpenAlexW4300594137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.