ArticleProceedings of the National Academy of Sciences of the United States of America2022
Stabilization of insect cell membranes and soluble enzymes by accumulated cryoprotectants during freezing stress.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 30 citations in OpenAlex.
- Whole testicular organ and seminal cryopreservation in the malarial mosquito Anopheles gambiae (Diptera: Culicidae).Journal of medical entomology · 2026Article
- Review
- Vulnerability of alpine butterfly eggs to early winter warming.Current research in insect science · 2026Article
- The influence of proline on surface interactions in aqueous solutions.Biophysical journal · 2025Article
- Physiological reprogramming during cold acclimation in the predatory mite Neoseiulus bicaudus.Experimental & applied acarology · 2025Article
- Trehalose accumulation contributes to enhanced cold stress tolerance in Telenomus remus, a dominant egg parasitoid of Spodoptera frugiperda.BMC genomics · 2025Article
- The Role of Heat Shock Proteins in Insect Stress Response, Immunity, and Climate Adaptation.Insects · 2025Review
- Assessing the efficacy of natural soil biotin on soil quality, microbial diversity, andFrontiers in microbiology · 2024Article
- Extracellular freezing induces a permeability transition in the inner membrane of muscle mitochondria of freeze-sensitive but not freeze-tolerantFrontiers in physiology · 2024Article
- High and Low Temperatures Differentially Affect Survival, Reproduction, and Gene Transcription in Male and Female Moths ofInsects · 2023Article
- Green Synthesis of Iron Oxide (Hematite) Nanoparticles and Their Influence onPlants (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most multicellular organisms are freeze sensitive, but the ability to survive freezing of the extracellular fluids evolved in several vertebrate ectotherms, some plants, and many insects. Here, we test the coupled hypotheses that are perpetuated in the literature: that irreversible denaturation of proteins and loss of biological membrane integrity are two ultimate molecular mechanisms of freezing injury in freeze-sensitive insects and that seasonally accumulated small cryoprotective molecules (CPs) stabilize proteins and membranes against injury in freeze-tolerant insects. Using the drosophilid fly,
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