ArticleProceedings of the National Academy of Sciences of the United States of America2022
Human cerebellum and corticocerebellar connections involved in emotional memory enhancement.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Pooled it
- Effects of stress-related neuromodulators on amygdala and hippocampus resting state functional connectivity.Journal of psychopharmacology (Oxford, England) · 2024Trial
- Movement-Anchored Emotional Memory: An Embodied Neuropsychological Framework.Journal of clinical medicine · 2026Review
- The role of the subcortical structures in subthreshold depression: evidence from static and dynamic functional connectivity.Brain structure & function · 2026Article
- Cerebellar oligodendrocytic α-synuclein pathology and dentate nucleus neuronal hypertrophy in Parkinson's disease.Scientific reports · 2026Article
- Disrupted Brain Connectivity in Newborns Following Antenatal Opioid Exposure.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Observational
- Ketogenic therapy as a potential novel treatment approach for PTSD: an integrative review and proposed mechanistic model.Frontiers in psychiatry · 2026Review
- Declined connectivity of thalamus and dorsomedial prefrontal cortex in post-stroke cognitive impairment delineated by lesion network mapping.Brain communications · 2026Article
- The Influence of Sex and Sex-Steroid Hormones on Cerebellar Structure and Functional Connectivity Across Adulthood.Human brain mapping · 2025Article
- Review
- Lithium salts alter the size and morphology of the Madagascar hissing cockroach's neuroendocrine system.Scientific reports · 2025Article
- Deviations From Normative Functioning Underlying Emotional Episodic Memory Revealed Cross-Scale Neurodiverse Alterations Linked to Affective Symptoms in Distinct Psychiatric Disorders.Biological psychiatry global open science · 2025Article
- The cerebellum and psychiatric disorders: unraveling its role in mental health.Arquivos de neuro-psiquiatria · 2025Review
- A neurofunctional signature of affective arousal generalizes across valence domains and distinguishes subjective experience from autonomic reactivity.Nature communications · 2025Article
- Cerebellar Micro Complex Model Using Histologic Boolean Mapping Simulates Adaptive Motor Control.Neuroinformatics · 2025Article
- Distribution and morphological features of astrocytes and Purkinje cells in the human cerebellum.Frontiers in neuroanatomy · 2025Article
- Functional cerebello-cortico-limbic connectivity in aggression: A resting-state 7T fMRI study in healthy volunteers.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Social and emotional learning in the cerebellum.Nature reviews. Neuroscience · 2024Review
- Purkinje cell ablation and Purkinje cell-specific deletion of Tsc1 in the developing cerebellum strengthen cerebellothalamic synapses.The Journal of physiology · 2024Article
- A neurofunctional signature of subjective disgust generalizes to oral distaste and socio-moral contexts.Nature human behaviour · 2024Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emotional information is better remembered than neutral information. Extensive evidence indicates that the amygdala and its interactions with other cerebral regions play an important role in the memory-enhancing effect of emotional arousal. While the cerebellum has been found to be involved in fear conditioning, its role in emotional enhancement of episodic memory is less clear. To address this issue, we used a whole-brain functional MRI approach in 1,418 healthy participants. First, we identified clusters significantly activated during enhanced memory encoding of negative and positive emotional pictures. In addition to the well-known emotional memory-related cerebral regions, we identified a cluster in the cerebellum. We then used dynamic causal modeling and identified several cerebellar connections with increased connection strength corresponding to enhanced emotional memory, including one to a cluster covering the amygdala and hippocampus, and bidirectional connections with a cluster covering the anterior cingulate cortex. The present findings indicate that the cerebellum is an integral part of a network involved in emotional enhancement of episodic memory.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.