Evidence map›Paper›PMID 36191183›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Feedback linking cell envelope stiffness, curvature, and synthesis enables robust rod-shaped bacterial growth.

Salem Al-Mosleh, Ajay Gopinathan, Christian D Santangelo, Kerwyn Casey Huang, Enrique R Rojas

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Sensing the shape of a surface by tightly surface-bound filaments.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Feedback linking cell envelope stiffness, curvature, and synthesis enables robust rod-shaped bacterial growth.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Salem Al-MoslehJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138.ORCID 0000-0002-6988-2991
Ajay GopinathanDepartment of Physics, University of California, Merced, CA 95343.ORCID 0000-0002-9369-8780
Christian D SantangeloDepartment of Physics, Syracuse University, Syracuse, NY 13210.
Kerwyn Casey HuangDepartment of Bioengineering, Stanford University, Stanford, CA 94305.ORCID 0000-0002-8043-8138
Enrique R RojasDepartment of Biology, New York University, New York, NY 10003.
Chan Zuckerberg Initiative (United States) · USHarvard University · USNew York University · USSyracuse University · USUniversity of California, Merced · US

Funding

Exploring mechanical mechanisms of antibiotic resistanceR35GM143057 · NIGMS · NEW YORK UNIVERSITY · PI ROJAS, ENRIQUE · 2021 to 2025
$1.9M
6 · The paper itself

Abstract

Bacterial growth is remarkably robust to environmental fluctuations, yet the mechanisms of growth-rate homeostasis are poorly understood. Here, we combine theory and experiment to infer mechanisms by which

Indexed as

Cell WallEscherichia coliBacteriaCell CycleFeedbackcell envelopecell mechanicsenvelope softeninghyperosmotic shockstored growth

Identifiers

PMID36191183
PMCPMC9564212
OpenAlexW4300594562

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.