Evidence map›Paper›PMID 36190557›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Clinical exercise therapy program with multiple myeloma patients: Impacts on feasibility, adherence and efficacy.

Michael Mendes Wefelnberg, Timo Niels, Udo Holtick, Franziska Jundt, Christoph Scheid, Freerk T Baumann

Open access · hybridAbstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 6 citations in OpenAlex.

  1. Exercise for myeloma patients with bone disease: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Review
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  4. Article
  5. Review
  6. Feasibility and safety of impact-loading exercise in patients with multiple myeloma-a pilot study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Michael Mendes WefelnbergDepartment I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany. michael.mendes-wefelnberg@uk-koeln.de.
Timo NielsDepartment I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Udo HoltickDepartment I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Franziska JundtMedical Clinic and Polyclinic II, Center for Internal Medicine, University Hospital Wuerzburg, Oberdürrbacher Straße 6, House A3, 97080, Würzburg, Germany.
Christoph ScheidDepartment I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Freerk T BaumannDepartment I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Dusseldorf, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Heinrich Heine University Düsseldorf · DEUniversity Hospital Cologne · DEDüsseldorf University Hospital · DEUniversitätsklinikum Würzburg · DE

Funding

Deutsche Forschungsgemeinschaft JU 426/6-1
6 · The paper itself

Abstract

purposeMultiple myeloma (MM) is a severe hemato-oncological disease with high mortality and increasing incidence rate. Since evidence on exercise therapy in MM patients remains limited, this study examines feasibility, adherence, and efficacy based on real-life data from an oncologic care structure.

methodsA data evaluation of MM patients who participated in the oncologic exercise and movement therapy (OTT) at the Cologne University Hospital between 2012 and 2019 was conducted. The patient flow was incrementally reduced to four cohorts, intention-to-treat cohort (ITTC), safety cohort (SC), adherence cohort (AC), and efficacy cohort (EC). Cohorts were evaluated descriptively and by means of correlation analysis as well as group and time comparisons.

resultsThirty patients registered at the OTT between 2012 and 2019 (ITTC). The SC (N = 26) attended exercise therapy on average about one session per week over a period of 8 months. One-third dropped out within 3 months. In the AC (N = 15), BMI at baseline exhibited a strong and very significant negative correlation with exercise adherence. In the EC (N = 8), a significant improvement in physical functioning and a tendency towards significance in fatigue reduction between two measurement points was observed. No adverse events were documented.

conclusionsThe present observatory study reveals safety and feasibility while indicating adherence and efficacy of exercising MM patients under real-life therapy circumstances. Found obstacles to exercising as well as improvements in questionnaire scale scores need to be further examined in confirmatory study designs.

Indexed as

Multiple MyelomaExerciseExercise TherapyFeasibility StudiesHumansSurveys and QuestionnairesAdherenceEfficacyFeasibilityMultiple myeloma (MM)

Identifiers

PMID36190557
PMCPMC9633464
OpenAlexW4300690249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.