Evidence map›Paper›PMID 36190429›Full record

ArticleMicrobiology spectrum2022

An Intrinsic Alkalization Circuit Turns on

Arunima Kalita, Rajesh Kumar Mishra, Vineet Kumar, Amit Arora, Dipak Dutta

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. ACS chemical biology · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Arunima KalitaCSIR Institute of Microbial Technology, Chandigarh, India.
Rajesh Kumar MishraCSIR Institute of Microbial Technology, Chandigarh, India.
Vineet KumarCSIR Institute of Microbial Technology, Chandigarh, India.
Amit AroraCSIR Institute of Microbial Technology, Chandigarh, India.
Dipak DuttaCSIR Institute of Microbial Technology, Chandigarh, India.ORCID 0000-0002-0458-4109
Institute of Microbial Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The trace metal manganese in excess affects iron-sulfur cluster and heme-protein biogenesis, eliciting cellular toxicity. The manganese efflux protein MntP is crucial to evading manganese toxicity in bacteria. Recently, two Mn-sensing riboswitches upstream of

Indexed as

Escherichia coli ProteinsRiboswitchAmmoniaEscherichia coliGene Expression Regulation, BacterialGlutamate-Ammonia LigaseHemeIronLigandsManganeseMembrane Transport ProteinsSulfurAmmoniaEscherichia coli ProteinsGlutamate-Ammonia LigaseHemeIronLigandsManganeseMembrane Transport ProteinsMntP protein, E coliRiboswitchSulfurammonia productionEscherichia coliglutaminasesglutamineglutamine synthetaseintrinsic alkalizationmanganese toxicitymntP riboswitchpH elevation

Identifiers

PMID36190429
PMCPMC9603457
OpenAlexW4300484888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.