Trial reportJournal of rehabilitation medicine2022
Comparison of Quadriceps and Hamstring Muscle Strength after Exercises with and without Blood Flow Restriction following Anterior Cruciate Ligament Surgery: A Randomized Controlled Trial.
Trial report in Journal of rehabilitation medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Blood flow restriction training for lower limb injury prevention and rehabilitation in dancers: a scoping review of current evidence and future directions.BMC sports science, medicine & rehabilitation · 2026Pooled it
- Comparative effectiveness of resistance training modalities after anterior cruciate ligament reconstruction: a network meta-analysis of randomized controlled trials.Frontiers in physiology · 2026Pooled it
- The effects of blood flow restriction training on early muscle strength and mid-term knee function following anterior cruciate ligament reconstruction: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- How effective is the addition of specific exercise therapy for patients after anterior cruciate ligament surgery? A systematic review and meta-analysis.Frontiers in physiology · 2025Pooled it
- Comparison of Blood Flow Restriction Interventions to Standard Rehabilitation After an Anterior Cruciate Ligament Injury: A Systematic Review.The American journal of sports medicine · 2024Pooled it
- The effects of short-term blood flow restriction training on knee function and quality of life in older adults patients with tibial plateau fractures.Scientific reports · 2026Trial
- Walking with blood flow restriction on lower limb muscles post-ACL reconstruction: A within-subject trial.PloS one · 2025Trial
- Blood Flow Restriction Training After Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis of Randomized Controlled Trials.Orthopaedic journal of sports medicine · 2026Review
- The Effectiveness of Blood Flow Restriction Training on Rehabilitation After Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2026Review
- Conservative treatment using blood flow restriction and brace in individuals with complete anterior cruciate ligament rupture: protocol for a randomised clinical trial.Journal of orthopaedic surgery and research · 2025Article
- Blood Flow Restriction Training Prior to and After Anterior Cruciate Ligament Reconstruction: A Scoping Review.Journal of functional morphology and kinesiology · 2025Review
- Current Narrative Review-Application of Blood Flow Restriction Exercise in Clinical Knee Problems.Medicina (Kaunas, Lithuania) · 2025Review
- Can Blood Flow Restriction Be the Key to Reducing Quadriceps Weakness in the Early and Mid-Phases After Anterior Cruciate Ligament Reconstruction with a Hamstring Graft? A Systematic Review of Randomized Controlled Trials.Diagnostics (Basel, Switzerland) · 2025Review
- Article
- Qualitative Evaluation of Patient Experiences with Low-Load Blood Flow Restriction and Heavy-Load Resistance Training Post-ACL Reconstruction.International journal of sports physical therapy · 2025Article
- Effectiveness of Keeogo Exoskeleton-Assisted Rehabilitation on Functional Mobility in Older Adults with Multimorbidity: A Single-Arm Pilot Study.International journal of general medicine · 2025Article
- Effect of blood flow restriction training in early postoperative rehabilitation after ACL reconstruction: a randomised controlled trial.Frontiers in sports and active living · 2025Article
- Blood Flow Restriction Training and Its Use in Rehabilitation After Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Commentary on "Comparison of Quadriceps and Hamstrings Muscle Strength after Exercises with and without Blood Flow Restriction Following Anterior Cruciate Ligament Surgery: A Randomized Controlled Trial".Journal of rehabilitation medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMuscle mass loss occurs following anterior cruciate ligament reconstruction surgery.
objectiveTo compare the gain in muscle strength in the quadriceps and hamstring muscles in patients following anterior cruciate ligament reconstruction surgery, using exercises with and without blood flow restriction.
methodsThis is a randomized controlled trial, in which 50% (n = 14) of the participants were allocated to the intervention group and the remaining 50% (n = 14) to the control group. The study included the participation of postoperative patients, with reconstruction of the anterior cruciate ligament.
resultsAfter comparing the rehabilitation of the groups, a statistical difference was observed in the quadriceps with an increase in muscle strength (p < 0.01) after 12 weeks and an increase in muscle strength hamstrings (p < 0.01) after 8 and 12 weeks in the injured legs of the intervention group compared to the control. In the analysis of the participants' physical function, there was an significant increase difference in the Lysholm questionnaire (p < 0.01) after 8 and 12 weeks, in the KOOS pain questionnaire (p < 0.01) after 4 weeks a decrease was observed, symptoms and daily activities (p < 0.01) after 8 and 12 weeks, quality of life (p < 0.01) after 12 weeks, and in the IKDC questionnaire (p < 0.01) after 8 and 12 weeks there was an significant increase difference of the intervention group compared to the control.
conclusionAfter anterior cruciate ligament surgery, exercises with blood flow restriction proved more efficient for improving the muscle strength of the quadriceps and hamstrings, and the physical function of the knee than the same exercises without blood flow restriction.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.