Evidence map›Paper›PMID 36190355›Full record

ReviewChemical Society reviews2022

Advancements in antimicrobial nanoscale materials and self-assembling systems.

Jack A Doolan, George T Williams, Kira L F Hilton, Rajas Chaudhari, John S Fossey, Benjamin T Goult, Jennifer R Hiscock

Abstract readReview
In one paragraph

Review in Chemical Society reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. ImidazoliumRSC advances · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Green Synthesis of Narrow-Size Silver Nanoparticles UsingInternational journal of molecular sciences · 2024
    Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jack A DoolanSchool of Chemistry and Forensic Science, University of Kent, Canterbury, Kent CT2 7NH, UK. J.R.Hiscock@Kent.ac.uk.ORCID http://orcid.org/0000-0003-2693-7515
George T WilliamsSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. G.T.Williams@Bham.ac.uk.ORCID http://orcid.org/0000-0001-6162-8895
Kira L F HiltonSchool of Chemistry and Forensic Science, University of Kent, Canterbury, Kent CT2 7NH, UK. J.R.Hiscock@Kent.ac.uk.
Rajas ChaudhariSchool of Chemistry and Forensic Science, University of Kent, Canterbury, Kent CT2 7NH, UK. J.R.Hiscock@Kent.ac.uk.
John S FosseySchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. G.T.Williams@Bham.ac.uk.ORCID http://orcid.org/0000-0002-2626-5117
Benjamin T GoultSchool of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK. B.T.Goult@Kent.ac.uk.ORCID http://orcid.org/0000-0002-3438-2807
Jennifer R HiscockSchool of Chemistry and Forensic Science, University of Kent, Canterbury, Kent CT2 7NH, UK. J.R.Hiscock@Kent.ac.uk.ORCID http://orcid.org/0000-0002-1406-8802

Funding

Medical Research Council MR/T020415/1
6 · The paper itself

Abstract

Antimicrobial resistance is directly responsible for more deaths per year than either HIV/AIDS or malaria and is predicted to incur a cumulative societal financial burden of at least $100 trillion between 2014 and 2050. Already heralded as one of the greatest threats to human health, the onset of the coronavirus pandemic has accelerated the prevalence of antimicrobial resistant bacterial infections due to factors including increased global antibiotic/antimicrobial use. Thus an urgent need for novel therapeutics to combat what some have termed the 'silent pandemic' is evident. This review acts as a repository of research and an overview of the novel therapeutic strategies being developed to overcome antimicrobial resistance, with a focus on self-assembling systems and nanoscale materials. The fundamental mechanisms of action, as well as the key advantages and disadvantages of each system are discussed, and attention is drawn to key examples within each field. As a result, this review provides a guide to the further design and development of antimicrobial systems, and outlines the interdisciplinary techniques required to translate this fundamental research towards the clinic.

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsBacteriaHumansAnti-Bacterial AgentsAnti-Infective Agents

Identifiers

PMID36190355
PMCPMC9575517

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.