Evidence map›Paper›PMID 36190251›Full record

ArticleApplied and environmental microbiology2022

Transcriptome and Metabolome Analysis Revealing the Improved ε-Poly-l-Lysine Production Induced by a Microbial Call from Botrytis cinerea.

Xin Zeng, Chen Zhang, Chaoping Yue, Zhiwei Su, Baoyan Tai, Hui Tang, Huawei Zeng, Bingyue Xin, Mingzhi Zhu

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xin Zeng *Anhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, Huaibei Normal Universitygrid.440755.7, Huaibei, China.ORCID 0000-0002-9708-5594
Chen Zhang *Anhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, Huaibei Normal Universitygrid.440755.7, Huaibei, China.
Chaoping YueAnhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, Huaibei Normal Universitygrid.440755.7, Huaibei, China.
Zhiwei SuAnhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, Huaibei Normal Universitygrid.440755.7, Huaibei, China.
Baoyan TaiAnhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, Huaibei Normal Universitygrid.440755.7, Huaibei, China.
Hui TangAnhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, Huaibei Normal Universitygrid.440755.7, Huaibei, China.
Huawei ZengAnhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, Huaibei Normal Universitygrid.440755.7, Huaibei, China.
Bingyue XinAnhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation, Huaibei Normal Universitygrid.440755.7, Huaibei, China.
Mingzhi ZhuNational Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, China.ORCID 0000-0003-2694-6278
Huaibei Normal University · CNHunan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ε-Poly-l-lysine (ε-PL) is a wide-spectrum antimicrobial agent, while its biosynthesis-inducing signals are rarely reported. This study found that Botrytis cinerea extracts could act as a microbial call to induce a physiological modification of Streptomyces albulus for ε-PL efficient biosynthesis and thereby resulted in ε-PL production (34.2 g/liter) 1.34-fold higher than control. The elicitors could be primary isolated by ethanol and butanol extraction, which resulted in more vibrant, aggregate and stronger mycelia. The elicitor-derived physiological changes focused on three aspects: ε-PL synthase, energy metabolism, and lysine biosynthesis. After elicitor addition, upregulated sigma factor

Indexed as

PolylysineTranscriptomeAdenosine DiphosphateAdenosine TriphosphateAnti-Bacterial AgentsButanolsCarbonCitrate (si)-SynthaseDiaminopimelic AcidEthanolFermentationHazardous SubstancesMetabolomeNADSigma FactorTricarboxylic AcidsAdenosine DiphosphateAdenosine TriphosphateAnti-Bacterial AgentsButanolsCarbonCitrate (si)-SynthaseDiaminopimelic AcidEthanolHazardous SubstancesNADPolylysineSigma FactorTricarboxylic AcidsBotrytis cinereafermentation optimizationmetabolome analysismicrobial elicitortranscriptional analysis

Identifiers

PMID36190251
PMCPMC9599581
OpenAlexW4300690651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.