Evidence map›Paper›PMID 36190143›Full record

ArticleVirulence2022

High frequency of CD8 escape mutations in elite controllers as new obstacle for HIV cure.

María A Navarrete-Muñoz, Ricardo Ramos, África Holguín, Alfonso Cabello, Miguel Górgolas, José M Benito, Norma Rallón

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virulence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

María A Navarrete-MuñozHIV and Viral Hepatitis Research Laboratory, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.
Ricardo RamosUnidad de Genómica, Scientific Park of Madrid, Madrid, Spain.
África HolguínHIV-1 Molecular Epidemiology Laboratory, Instituto Ramón y Cajal de Investigación Sanitaria(IRYCIS), Madrid, Spain.
Alfonso CabelloDivision of Infectious Diseases, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
Miguel GórgolasDivision of Infectious Diseases, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
José M BenitoHIV and Viral Hepatitis Research Laboratory, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.ORCID 0000-0002-7172-049X
Norma RallónHIV and Viral Hepatitis Research Laboratory, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Universidad Autónoma de Madrid (IIS-FJD, UAM), Madrid, Spain.ORCID 0000-0002-4643-247X
Hospital Universitario Rey Juan Carlos · ESHospital Universitario Fundación Jiménez Díaz · ESInstituto Ramón y Cajal de Investigación Sanitaria · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulation of mutations in epitopes of cytolytic-

Indexed as

HIV-1HIV InfectionsElite ControllersEpitopesgag Gene Products, Human Immunodeficiency VirusHumansMutationT-Lymphocytes, CytotoxicEpitopesgag Gene Products, Human Immunodeficiency VirusCTL responseelite controllersHIV-Gag proviral DNAHIV reservoirnext generation sequencing (NGS)resting memory CD4+ T-cells

Identifiers

PMID36190143
PMCPMC9543107
OpenAlexW4300690189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.