Evidence map›Paper›PMID 36189892›Full record

ArticleNucleic acids research2023

microbioTA: an atlas of the microbiome in multiple disease tissues of Homo sapiens and Mus musculus.

Ping Wang, Sainan Zhang, Guoyou He, Meiyu Du, Changlu Qi, Ruyue Liu, Siyuan Zhang, Liang Cheng, Lei Shi, Xue Zhang

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ping WangCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, Heilongjiang, China.ORCID 0000-0003-4451-1585
Sainan ZhangCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, Heilongjiang, China.
Guoyou HeCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, Heilongjiang, China.
Meiyu DuCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, Heilongjiang, China.
Changlu QiCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, Heilongjiang, China.
Ruyue LiuCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, Heilongjiang, China.
Siyuan ZhangDepartment of Anatomy, College of Basic Medical Sciences, Harbin Medical University, Harbin 150081, Heilongjiang, China.
Liang ChengCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, Heilongjiang, China.ORCID 0000-0002-6665-6710
Lei ShiNHC Key Laboratory of Molecular Probes and Targeted Diagnosis and Therapy, Harbin Medical University, Harbin 150028, Heilongjiang, China.
Xue ZhangNHC Key Laboratory of Molecular Probes and Targeted Diagnosis and Therapy, Harbin Medical University, Harbin 150028, Heilongjiang, China.
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

microbioTA (http://bio-annotation.cn/microbiota) was constructed to provide a comprehensive, user-friendly resource for the application of microbiome data from diseased tissues, helping users improve their general knowledge and deep understanding of tissue-derived microbes. Various microbes have been found to colonize cancer tissues and play important roles in cancer diagnoses and outcomes, with many studies focusing on developing better cancer-related microbiome data. However, there are currently no independent, comprehensive open resources cataloguing cancer-related microbiome data, which limits the exploration of the relationship between these microbes and cancer progression. Given this, we propose a new strategy to re-align the existing next-generation sequencing data to facilitate the mining of hidden sequence data describing the microbiome to maximize available resources. To this end, we collected 417 publicly available datasets from 25 human and 14 mouse tissues from the Gene Expression Omnibus database and use these to develop a novel pipeline to re-align microbiome sequences facilitating in-depth analyses designed to reveal the microbial profile of various cancer tissues and their healthy controls. microbioTA is a user-friendly online platform which allows users to browse, search, visualize, and download microbial abundance data from various tissues along with corresponding analysis results, aimimg at providing a reference for cancer-related microbiome research.

Indexed as

MicrobiotaNeoplasmsAnimalsDatabases, GeneticHumansMiceOrgan SpecificityPhylogeny

Identifiers

PMID36189892
PMCPMC9825499
OpenAlexW4300690536

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.