ArticleStatistical methods in medical research2022
Online control of the False Discovery Rate in group-sequential platform trials.
Article in Statistical methods in medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Asymptotic online FWER control for dependent test statistics.Statistical methods in medical research · 2026Article
- On the Inclusion of Non-Concurrent Controls in Platform Trials With an Interim Analysis.Statistics in medicine · 2026Article
- Randomization in the age of platform trials: unexplored challenges and some potential solutions.BMC medical research methodology · 2025Review
- ADDIS-Graphs for Online Error Control With Application to Platform Trials.Biometrical journal. Biometrische Zeitschrift · 2025Article
- Why and how should we simulate platform trials? Learnings from EU-PEARL.BMC medical research methodology · 2025Article
- Current state-of-the-art and gaps in platform trials: 10 things you should know, insights from EU-PEARL.EClinicalMedicine · 2024Review
- Online multiple hypothesis testing.Statistical science : a review journal of the Institute of Mathematical Statistics · 2023Article
- Online error rate control for platform trials.Statistics in medicine · 2023Article
- The population-wise error rate for clinical trials with overlapping populations.Statistical methods in medical research · 2023Article
- Designing an exploratory phase 2b platform trial in NASH with correlated, co-primary binary endpoints.PloS one · 2023Article
- Design Considerations for a Phase II Platform Trial in Major Depressive Disorder.Pharmaceutical statisticsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When testing multiple hypotheses, a suitable error rate should be controlled even in exploratory trials. Conventional methods to control the False Discovery Rate assume that all
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.