Evidence map›Paper›PMID 36189434›Full record

ReviewArabian journal of chemistry2022

Unraveling the mystery of efficacy in Chinese medicine formula: New approaches and technologies for research on pharmacodynamic substances.

Yaolei Li, Zhijian Lin, Yu Wang, Shanshan Ju, Hao Wu, Hongyu Jin, Shuangcheng Ma, Bing Zhang

Abstract readReview
In one paragraph

Review in Arabian journal of chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Additive manufacturing in nano drug delivery systems.Pharmaceutical science advances · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yaolei LiSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China.
Zhijian LinSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China.
Yu WangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China.
Shanshan JuSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China.
Hao WuSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China.
Hongyu JinNational Institutes for Food and Drug Control, Beijing 102629, China.
Shuangcheng MaNational Institutes for Food and Drug Control, Beijing 102629, China.
Bing ZhangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional Chinese medicine (TCM) is the key to unlock treasures of Chinese civilization. TCM and its compound play a beneficial role in medical activities to cure diseases, especially in major public health events such as novel coronavirus epidemics across the globe. The chemical composition in Chinese medicine formula is complex and diverse, but their effective substances resemble "mystery boxes". Revealing their active ingredients and their mechanisms of action has become focal point and difficulty of research for herbalists. Although the existing research methods are numerous and constantly updated iteratively, there is remain a lack of prospective reviews. Hence, this paper provides a comprehensive account of existing new approaches and technologies based on previous studies with an

Indexed as

2D, Two Dimensional3D, Three DimensionalActive ingredientADME, Absorption, Distribution, Metabolism, and ExcretionAFA DESI-MSI, Air flow-assisted desorption electrospray ionization mass spectrometry imagingAI, Artificial IntelligenceCDE, Center for Drug EvaluationChemical componentsChinese medicine formulaCompoundCOX-2, Cyclooxygenase 2Disease TargetsGC-MS, Gas chromatography-mass spectrometryHPLC, High Performance Liquid ChromatographyHR-MS, High Resolution Mass SpectrometryHTS, High Throughput ScreeningHUA, hyperuricemiaICPMS, inductively coupled plasma mass spectrometryMALDI MS, Matrix for surface-assisted laser desorption/ionization mass spectrometryMass SpectrometryMD, MicrodialysisMI, Molecular imprintingMSI, Mass spectrometry imagingNL/PR, Neutral loss/precursor ionNMPA, National Medical Products AdministrationOPLS-DA, Orthogonal partial least squares discriminant analysisPD, PharmacodynamicPK, PharmacokineticQqQ-MS, Triple quadruple mass spectrometryQSAR, Quantitative structure-activity relationshipQ-TOF/MS, Quadrupole time-of-flight mass spectrometryR-strategy, Reduce strategyTCM, Traditional Chinese medicineUF, Affinity ultrafiltrationUPLC, Ultra Performance Liquid ChromatographyXO, Xanthine oxidase

Identifiers

PMID36189434
PMCPMC9514000

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.