Evidence map›Paper›PMID 36189388›Full record

ArticleFrontiers in surgery2022

The effect of intravenous lidocaine on propofol dosage in painless bronchoscopy of patients with COPD.

Li Yang, Tao He, Min-Xiao Liu, Shi-Qiang Han, Zhi-Ang Wu, Wei Hao, Zhi-Xia Lu

Abstract read
In one paragraph

Article in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Anesthesia for Bronchoscopy-An Update.Journal of clinical medicine · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Li YangDepartment of Anesthesiology, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang, China.
Tao HeDepartment of Anesthesiology, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang, China.
Min-Xiao LiuDepartment of Anesthesiology, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang, China.
Shi-Qiang HanDepartment of Radiotherapy, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang, China.
Zhi-Ang WuDepartment of Anesthesiology, Luquan Second People's Hospital, Shijiazhuang, China.
Wei HaoDepartment of Anesthesiology, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang, China.
Zhi-Xia LuDepartment of Anesthesiology, Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We tested the hypothesis that intravenous (IV) lidocaine reduces propofol requirements in painless bronchoscopy in patients with chronic obstructive pulmonary disease (COPD). Methods: A total of 93 patients who underwent bronchoscopy were included in this randomized placebo-controlled study. The patients were randomly divided into two groups. After the IV doses of nalbuphine, patients were given a bolus of propofol, which was titrated if necessary until loss of consciousness. Then patients were given IV lidocaine (2 mg/kg then 4 mg/kg/h) or the same volume of saline. The primary endpoint was the propofol requirements. Secondary endpoints were the incidence of hypoxemia, the incidence of cough during glottis examination, the systolic blood pressure (SBP) and heart rate (HR) during bronchoscopy procedures, the bronchoscopist's comforts, and the time for wakefulness before recovery. Results: Lidocaine infusion resulted in a significant reduction in propofol requirements ( Conclusion: In painless bronchoscopy in patients with COPD, IV infusion of lidocaine resulted in a reduction in propofol dose requirements and reduce the incidence of adverse events.

Indexed as

bronchoscopyhypoxemialidocainepropofolsedation

Identifiers

PMID36189388
PMCPMC9520192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.