ArticleFrontiers in surgery2022
Clinical study on multi-focused laser in the treatment of vulvar lichen sclerosus.
Article in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and Safety of Laser Treatment in Vulvar Lichen Sclerosus: A Systematic Review.Lasers in surgery and medicine · 2025Pooled it
- One-year outcome after laser treatment of vulvar lichen sclerosus: a prospective observational trial.Archives of gynecology and obstetrics · 2026Trial
- Two-year follow-up of women with lichen sclerosus treated with laser therapy: A prospective observational study.Lasers in medical science · 2026Observational
- Clinical Outcomes of Fractional Carbon Dioxide Laser Treatment in Women With Vulvar Lichen Simplex Chronicus: A Retrospective Study With 12-Month Follow-Up.Lasers in surgery and medicine · 2026Article
- Lichen sclerosus. Part 2. Guideline of the DGG, DGGG, OEGGG and SGGG (S3-Level, AWMF Registry No. 013-105, July 2025.Geburtshilfe und Frauenheilkunde · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To investigate the clinical effect of Multi-focused (MF) laser in the treatment of vulvar lichen sclerosus (VLS). Methods: In this single-center, randomized controlled trial, we compared the effect of fractionated MF laser with other treatments on patients with biopsy-proven VLS. Patients with VLS were enrolled in this study and randomly divided into three groups. Patients in the experimental group were treated with a CO Results: One month after treatment, the pruritus degree, skin elasticity, skin color, lesion scope, and total score decreased in the experimental group, and the differences were statistically significant ( Conclusion: For the three treatment methods for VLS, topical corticosteroids + traditional Chinese medicine can quickly relieve itching symptoms in patients, but it cannot significantly improve skin elasticity, skin color, and lesion scope, and VLS easily relapses after treatment. Radiofrequency can improve itching symptoms and skin color but has poor effects on the change of skin elasticity and lesion scope. Multi-focused laser treatment can alleviate the degree of pruritus, improve skin color and elasticity, and narrow the lesion scope, and VLS will not relapse within three months after treatment.
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Registered trials
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