Evidence map›Paper›PMID 36189368›Full record

ArticleFrontiers in cellular and infection microbiology2022

Psychological stress creates an immune suppressive environment in the lung that increases susceptibility of aged mice to

William P Lafuse, Qian Wu, Naresh Kumar, Noushin Saljoughian, Shrayes Sunkum, Omar Santiagonunez Ahumada, Joanne Turner, Murugesan V S Rajaram

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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  7. CD4International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

William P LafuseDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
Qian WuDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
Naresh KumarDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
Noushin SaljoughianDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
Shrayes SunkumDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
Omar Santiagonunez AhumadaDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
Joanne TurnerHost Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX, United States.
Murugesan V S RajaramDepartment of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, United States.
The Ohio State University · USTexas Biomedical Research Institute · US

Funding

Molecular mechanism of cardiac inflammation and dysfunction in Pseudomonas aeruginosa infectionR01AI146252 · NIAID · OHIO STATE UNIVERSITY · PI RAJARAM, MURUGESAN · 2019 to 2023
$2.2M
Role of Aging on cardiac macrophage dysfunction and heart failure during infectionR21AG073720 · NIA · OHIO STATE UNIVERSITY · PI RAJARAM, MURUGESAN · 2022 to 2023
$433k
NIAID NIH HHS R01 AI146252NIA NIH HHS R21 AG073720
6 · The paper itself

Abstract

Age is a major risk factor for chronic infections, including tuberculosis (TB). Elderly TB patients also suffer from elevated levels of psychological stress. It is not clear how psychological stress impacts immune response to

Indexed as

Mycobacterium tuberculosisTuberculosisAnimalsCytokinesIntegrin alpha2Interleukin-10LungMiceRNA, MessengerStress, PsychologicalCytokinesIntegrin alpha2Interleukin-10RNA, MessengeraginggranulomaIL10inflammagingMycobacterium tuberculosissocial stress

Identifiers

PMID36189368
PMCPMC9523253
OpenAlexW4296048698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.