Evidence map›Paper›PMID 36189366›Full record

ArticleFrontiers in cellular and infection microbiology2022

Longitudinal impact of asymptomatic malaria/HIV-1 co-infection on

Ashleigh Roberds, Carolyne Kifude, Janet Oyieko, Stephen Ocholla, James Mutunga, David Oullo, Charles Waga, Zhaozhang Li, Shirley Luckhart, V Ann Stewart

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ashleigh RoberdsDepartment of Preventive Medicine and Biostatistics, Division of Global Public Health, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
Carolyne KifudeKombewa Clinical Research Center, Kenya Medical Research Institute - United States Army Medical Research Directorate - Africa, Kisumu, Kenya.
Janet OyiekoKombewa Clinical Research Center, Kenya Medical Research Institute - United States Army Medical Research Directorate - Africa, Kisumu, Kenya.
Stephen OchollaKombewa Clinical Research Center, Kenya Medical Research Institute - United States Army Medical Research Directorate - Africa, Kisumu, Kenya.
James MutungaDepartment of Entomology and Vector Biology, United States Army Medical Research Directorate - Africa/Kenya Medical Research Institute, Kisumu, Kenya.
David OulloDepartment of Entomology and Vector Biology, United States Army Medical Research Directorate - Africa/Kenya Medical Research Institute, Kisumu, Kenya.
Charles WagaDepartment of Entomology and Vector Biology, United States Army Medical Research Directorate - Africa/Kenya Medical Research Institute, Kisumu, Kenya.
Zhaozhang LiBiomedical Instrumentation Center, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
Shirley LuckhartDepartment of Entomology, Plant Pathology and Nematology and Department of Biological Sciences, University of Idaho, Moscow, ID, United States.
V Ann StewartDepartment of Preventive Medicine and Biostatistics, Division of Global Public Health, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
Kenya Medical Research Institute · KEUniformed Services University of the Health Sciences · USUnited States Army Medical Research Directorate - Africa · KEUniversity of Idaho · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite significant developments towards malaria reduction, parasite transmission in the common context of HIV-1 co-infection and treatment for one or both infections has not been fully characterized. This is particularly important given that HIV-1 and malaria chemotherapies have the potential to alter gametocyte burden and mosquito infectivity. In this study, we examined 782 blood samples collected from a longitudinal cohort of 300 volunteers with asymptomatic parasitemia seeking HIV testing or treatment in the endemic region of Kisumu, Kenya, to define the impacts of HIV-1-malaria co-infection, antiretroviral therapy (ART) plus trimethoprim-sulfamethoxazole (TS) and the antimalarials artemether/lumefantrine (AL) on

Indexed as

AnophelesAntimalarialsCoinfectionHIV-1HIV InfectionsMalariaMalaria, FalciparumAnimalsArtemetherArtemether, Lumefantrine Drug CombinationHumansParasitemiaPlasmodium falciparumRNA, Ribosomal, 18STrimethoprim, Sulfamethoxazole Drug CombinationAntimalarialsArtemetherArtemether, Lumefantrine Drug CombinationRNA, Ribosomal, 18STrimethoprim, Sulfamethoxazole Drug Combinationco-infectionddPCRgametocytesHIVmalariamosquito infectivityplasmodium falciparumtransmission

Identifiers

PMID36189366
PMCPMC9523792
OpenAlexW4296173377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.