Evidence map›Paper›PMID 36189350›Full record

ArticleFrontiers in cellular and infection microbiology2022

Fecal microbiota in patients with a stoma decreases anaerobic bacteria and alters taxonomic and functional diversities.

Shunsuke A Sakai, Masato Aoshima, Kentaro Sawada, Satoshi Horasawa, Ayumu Yoshikawa, Takao Fujisawa, Shigenori Kadowaki, Tadamichi Denda, Nobuhisa Matsuhashi, Hisateru Yasui and 11 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 11 institutions in 1 country.

Shunsuke A SakaiGraduate School of Frontier Science, Department of Integrated Biosciences, University of Tokyo, Kashiwa, Japan.
Masato AoshimaGraduate School of Frontier Science, Department of Integrated Biosciences, University of Tokyo, Kashiwa, Japan.
Kentaro SawadaDepartment of Medical Oncology, Kushiro Rosai Hospital, Kushiro, Japan.
Satoshi HorasawaTranslational Research Support Section, National Cancer Center Hospital East, National Cancer Center Hospital East, Kashiwa, Japan.
Ayumu YoshikawaDepartment of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Takao FujisawaDepartment Head and Neck Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Shigenori KadowakiDepartment of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
Tadamichi DendaDivisioin of Gastroenterology, Chiba Cancer Center, Chiba, Japan.
Nobuhisa MatsuhashiDepartment of Gastroenterological surgery Pediatric surgery, Gifu University Hospital, Gifu, Japan.
Hisateru YasuiDepartment of Medical Oncology, Kobe City Medical Center General Hospital, Kobe, Japan.
Masahiro GotoCancer Chemotherapy Center, Osaka Medical and Pharmaceutical University Hospital, Takatsuki, Japan.
Kentaro YamazakiDivision of Gastrointestinal Oncology, Shizuoka Cancer Center, Shizuoka, Japan.
Yoshito KomatsuDepartment of Cancer Center, Hokkaido University Hospital, Hokkaido, Japan.
Ryota NakanishiDepartment of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Yoshiaki NakamuraTranslational Research Support Section, National Cancer Center Hospital East, National Cancer Center Hospital East, Kashiwa, Japan.
Hideaki BandoTranslational Research Support Section, National Cancer Center Hospital East, National Cancer Center Hospital East, Kashiwa, Japan.
Yamato HamayaGraduate School of Frontier Science, Department of Integrated Biosciences, University of Tokyo, Kashiwa, Japan.
Shun-Ichiro KageyamaDepartment of Radiation Oncology and Particle Therapy, National Cancer Center Hospital East, Kashiwa, Japan.
Takayuki YoshinoDepartment of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Katsuya TsuchiharaGraduate School of Frontier Science, Department of Integrated Biosciences, University of Tokyo, Kashiwa, Japan.
Riu YamashitaDivision of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan.
National Cancer Center Hospital East · JPAichi Cancer Center · JPChiba Cancer Center · JPGifu University Hospital · JPHokkaido University Hospital · JPKobe City Medical Center General Hospital · JPKushiro Rosai Hospital · JPKyushu University · JPOsaka University of Pharmaceutical Sciences · JPShizuoka Cancer Center · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the most common malignant diseases. Generally, stoma construction is performed following surgery for the resection of the primary tumor in patients with CRC. The association of CRC with the gut microbiota has been widely reported, and the gut microbiota is known to play an important role in the carcinogenesis, progression, and treatment of CRC. In this study, we compared the microbiota of patients with CRC between with and without a stoma using fecal metagenomic sequencing data from SCRUM-Japan MONSTAR-SCREEN, a joint industry-academia cancer research project in Japan. We found that the composition of anaerobes was reduced in patients with a stoma. In particular, the abundance of

Indexed as

Colorectal NeoplasmsMicrobiotaBacteria, AnaerobicFatty Acids, VolatileFecesHumansMethaneRNA, Ribosomal, 16SFatty Acids, VolatileMethaneRNA, Ribosomal, 16S16S rRNA geneanaerobecolorectal cancercolostomygut microbiotastoma

Identifiers

PMID36189350
PMCPMC9515963
OpenAlexW4295575861

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.