Evidence map›Paper›PMID 36189345›Full record

ReviewFrontiers in cellular and infection microbiology2022

Stealthy microbes: How

Julie Lynn Stoudenmire, Ashley Nicole Greenawalt, Cynthia Nau Cornelissen

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Norepinephrine derepresses the Fur regulon ofJournal of bacteriology · 2026
    Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julie Lynn StoudenmireCenter for Translational Immunology, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, United States.
Ashley Nicole GreenawaltCenter for Translational Immunology, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, United States.
Cynthia Nau CornelissenCenter for Translational Immunology, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, United States.

Funding

Using gonococcal TonB-dependent transporters as vaccine antigensU19AI144182 · NIAID · GEORGIA STATE UNIVERSITY · PI CORNELISSEN, CYNTHIA N · 2019 to 2023
$9.3M
Neisseria gonorrhoeae metal transporters that subvert nutritional immunityR01AI127793 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI CYNTHIA N CORNELISSEN, Alison K Criss · 2017 to 2026
$6.8M
Rational design of transferrin binding protein-based vaccines to combat gonorrheaR01AI125421 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI CORNELISSEN, CYNTHIA N, GRAY-OWEN, SCOTT D · 2017 to 2021
$3.1M
Iron acquisition mechanisms utilized by Neisseria gonorrhoeaeR01AI084400 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI CORNELISSEN, CYNTHIA N · 2009 to 2010
$674k
NIAID NIH HHS R01 AI084400NIAID NIH HHS R01 AI125421NIAID NIH HHS R01 AI127793NIAID NIH HHS U19 AI144182
6 · The paper itself

Abstract

Transition metals are essential for metalloprotein function among all domains of life. Humans utilize nutritional immunity to limit bacterial infections, employing metalloproteins such as hemoglobin, transferrin, and lactoferrin across a variety of physiological niches to sequester iron from invading bacteria. Consequently, some bacteria have evolved mechanisms to pirate the sequestered metals and thrive in these metal-restricted environments.

Indexed as

GonorrheaMetalloproteinsHemoglobinsHumansIronLactoferrinNeisseria gonorrhoeaeHemoglobinsIronLactoferrinMetalloproteinshemoglobinironlactoferrinNeisseria gonorrhoeaenutritional immunitysiderophoretransferrin

Identifiers

PMID36189345
PMCPMC9519893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.