Evidence map›Paper›PMID 36189343›Full record

ArticleFrontiers in cellular and infection microbiology2022

Deep metagenomic characterization of gut microbial community and function in preeclampsia.

Li-Juan Lv, Sheng-Hui Li, Ji-Ying Wen, Guang-Yang Wang, Hui Li, Tian-Wen He, Qing-Bo Lv, Man-Chun Xiao, Hong-Li Duan, Min-Chai Chen and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
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  9. PasteurizedMicroorganisms · 2024
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  12. Scoping Review of Microbiota Dysbiosis and Risk of Preeclampsia.American journal of reproductive immunology (New York, N.Y. : 1989) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Li-Juan LvMedical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China.
Sheng-Hui LiPuensum Genetech Institute, Wuhan, China.
Ji-Ying WenDepartment of Obstetric, Guangdong Women and Children Hospital, Guangzhou, China.
Guang-Yang WangDepartment of Microbiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Hui LiDepartment of Obstetric, Guangdong Women and Children Hospital, Guangzhou, China.
Tian-Wen HeMedical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China.
Qing-Bo LvPuensum Genetech Institute, Wuhan, China.
Man-Chun XiaoDepartment of Microbiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Hong-Li DuanDepartment of Obstetric, Guangdong Women and Children Hospital, Guangzhou, China.
Min-Chai ChenMedical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China.
Zhou-Ting YiDepartment of Obstetric, Guangdong Women and Children Hospital, Guangzhou, China.
Qiu-Long YanDepartment of Microbiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Ai-Hua YinMedical Genetic Center, Guangdong Women and Children Hospital, Guangzhou, China.
Guangdong Province Women and Children Hospital · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preeclampsia (PE) is a pregnancy complication characterized by severe hypertension and multiple organ damage. Gut microbiota has been linked to PE by previous amplicon sequencing studies. To resolve the PE gut microbiota in a higher taxonomy resolution, we performed shotgun metagenomic sequencing on the fecal samples from 40 early-onset PE and 37 healthy pregnant women. We recovered 1,750 metagenome-assembled genomes (representing 406 species) from the metagenomic dataset and profiled their abundances. We found that PE gut microbiota had enriched in some species belonging to

Indexed as

BacteriocinsMicrobiotaPorphyrinsPre-EclampsiaBacitracinBiomarkersChlorophyllDysbiosisFecesFemaleFolic AcidHumansMetagenomePregnancyPyridoxal PhosphateRhamnoseBacitracinBacteriocinsBiomarkersChlorophyllFolic AcidPorphyrinsPyridoxal PhosphateRhamnoseRiboflavinRNA, Ribosomal, 16Sgut microbiomemicrobial dysbiosismicrobial functionpreeclampsiapregnancyshotgun metagenomic sequencing

Identifiers

PMID36189343
PMCPMC9515455
OpenAlexW4295809201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.