ArticleInternational journal of nephrology and renovascular disease2022
Post-Operative Kidney Function Using Deep Hypothermic Circulatory Arrest (DHCA) in Aortic Arch Operation.
Article in International journal of nephrology and renovascular disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Sustained postoperative elevation of ionized magnesium levels following cardiac surgery with magnesium-enriched cardioplegia: a prospective observational study.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2026Observational
- Circulatory arrest time above 30 min have significantly detrimental effects on the outcomes of type a aortic dissection repair.Journal of cardiothoracic surgery · 2026Article
- Performance of Cleveland, Mehta, and Simplified Renal Index scores for predicting dialysis-requiring acute kidney injury after aorticRenal failure · 2025Article
- Cardiac surgery-associated acute kidney injury in cardiopulmonary bypass: a focus on sex differences and preventive strategies.American journal of physiology. Renal physiology · 2024Review
- Risk factors and outcome of aortic surgery patients with hypothermic circulatory arrest: can urine NGAL predict acute kidney injury?Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2024Article
- TAK-242 protects against oxygen-glucose deprivation and reoxygenation-induced injury in brain microvascular endothelial cells and alters the expression pattern of lncRNAs.Journal of thoracic disease · 2023Article
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6 authors.
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Abstract
Background: Although deep hypothermic circulatory arrest (DHCA) is a useful option to protect the central nervous system during aortic arch operations, the influence of simultaneous renal ischemia remains controversial. Patients and Methods: This is a retrospective observational study. Sixty-three patients who underwent thoracic aortic surgery with DHCA and 24 patients who underwent cardiac surgery without DHCA were included in this study. The mean age, preoperative serum creatinine (Cr) level, preoperative estimated glomerular filtration rate (eGFR), peak serum Cr level up to 48 hrs post-operative, elevation rate of Cr compared to the preoperative serum Cr, urine volume rate up to 48 hrs post-operative and AKI staging using the KDIGO criteria were estimated for each patient. Clinical parameters for 3 months after the operation and the 3-month post-operative mortality rate were assessed. Mean values indicating kidney function or distribution of the AKI stages were compared between patients with and without DHCA. Patients with DHCA were further divided according to the duration of ischemia to compare the values for the kidney function of each group, distribution of AKI stages and mortality. Results: The parameters indicating AKI of the patients with DHCA were significantly more severe than those without DHCA. Patients who had undergone an ischemic state for more than 40 min revealed significantly higher peak serum Cr, elevation rate of serum Cr, less urine volume up to 48 hrs post-operative compared with those without DHCA. Distribution of the AKI stages was related to the duration of ischemia. The 3-month post-operative mortality of the patients with DHCA was significantly higher than those without DHCA. Limitations: This study had limitations such as its retrospective design and small number patients, and the data will be required confirmation with other prospective studies. Conclusion: DHCA is closely related to AKI up to 48 hrs post-operative and death during the 3 months following surgery.
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