Evidence map›Paper›PMID 36189306›Full record

ArticleFrontiers in immunology2022

Acute exercise mobilizes NKT-like cells with a cytotoxic transcriptomic profile but does not augment the potency of cytokine-induced killer (CIK) cells.

Tiffany M Zúñiga, Forrest L Baker, Kyle A Smith, Helena Batatinha, Branden Lau, Michael P Gustafson, Emmanuel Katsanis, Richard J Simpson

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06643221 (Exercise-induced Adrenergic Receptor Signaling as an Immune Adjuvant for Allogeneic Cell Therapies), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06643221 early_phase1recruitingnot on this map

Exercise-induced Adrenergic Receptor Signaling as an Immune Adjuvant for Allogeneic Cell Therapies

TypeinterventionalSponsorUniversity of ArizonaRan2018 to 2031Enrolled200ConditionsLeukemia, Hematopoetic Stem Cell Transplantation, Donor Lymphocyte Infusion, CAR T-Cell TherapyArmsExercise, Isoproterenol, Placebo, Bisoprolol Fumarate Tablet 10 mg, Nadolol (1 x 80 mg) Tablets (Invamed, Inc)
3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tiffany M ZúñigaSchool of Nutritional Sciences and Wellness, The University of Arizona, Tucson, AZ, United States.
Forrest L BakerSchool of Nutritional Sciences and Wellness, The University of Arizona, Tucson, AZ, United States.
Kyle A SmithSchool of Nutritional Sciences and Wellness, The University of Arizona, Tucson, AZ, United States.
Helena BatatinhaSchool of Nutritional Sciences and Wellness, The University of Arizona, Tucson, AZ, United States.
Branden LauUniversity of Arizona Genetics Core, The University of Arizona, Tucson, AZ, United States.
Michael P GustafsonLaboratory Medicine and Pathology, Mayo Clinic Arizona, Phoenix, AZ, United States.
Emmanuel KatsanisDepartment of Pediatrics, The University of Arizona, Tucson, AZ, United States.
Richard J SimpsonSchool of Nutritional Sciences and Wellness, The University of Arizona, Tucson, AZ, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD3

Indexed as

Cytokine-Induced Killer CellsNeoplasmsCytotoxicity, ImmunologicExerciseHumansInterleukin-2Muromonab-CD3TranscriptomeInterleukin-2Muromonab-CD3cancercell therapycytotoxicitydonor lymphocyte infusionsexercise immunologyhematological malignanciesphysical activitysingle cell RNA sequencing

Identifiers

PMID36189306
PMCPMC9519182

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.