Evidence map›Paper›PMID 36189274›Full record

ArticleFrontiers in immunology2022

The role of mucosal-associated invariant T cells in visceral leishmaniasis.

Marcela de Lima Moreira, Luana Oliveira Borges-Fernandes, Marcelo Antônio Pascoal-Xavier, Ágata Lopes Ribeiro, Victória Hellena Silva Pereira, Troi Pediongco, Márcio Sobreira da Silva Araújo, Andréa Teixeira-Carvalho, Andrea Lucchesi de Carvalho, Maria Vitória Assumpção Mourão and 12 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
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  6. CD4Frontiers in immunology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 6 institutions in 3 countries.

Marcela de Lima MoreiraRené Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ-MINAS), Belo Horizonte, Minas Gerais, Brazil.
Luana Oliveira Borges-FernandesRené Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ-MINAS), Belo Horizonte, Minas Gerais, Brazil.
Marcelo Antônio Pascoal-XavierRené Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ-MINAS), Belo Horizonte, Minas Gerais, Brazil.
Ágata Lopes RibeiroRené Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ-MINAS), Belo Horizonte, Minas Gerais, Brazil.
Victória Hellena Silva PereiraRené Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ-MINAS), Belo Horizonte, Minas Gerais, Brazil.
Troi PediongcoDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Márcio Sobreira da Silva AraújoRené Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ-MINAS), Belo Horizonte, Minas Gerais, Brazil.
Andréa Teixeira-CarvalhoRené Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ-MINAS), Belo Horizonte, Minas Gerais, Brazil.
Andrea Lucchesi de CarvalhoJoão Paulo II Children's Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Maria Vitória Assumpção MourãoJoão Paulo II Children's Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Flávia Alves CamposJoão Paulo II Children's Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Marineide BorgesJoão Paulo II Children's Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Mariângela CarneiroParasitology Department, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Zhenjun ChenDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Eleanor SaundersDepartment of Biochemistry and Molecular Biology, The University of Melbourne, Melbourne, VIC, Australia.
Malcolm McConvilleDepartment of Biochemistry and Molecular Biology, The University of Melbourne, Melbourne, VIC, Australia.
Moriya TsujiAaron Diamond AIDS Research Center, Department of Medicine, Columbia University Irving Medical Center, New York, NY, United States.
James McCluskeyDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Olindo Assis Martins-FilhoRené Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ-MINAS), Belo Horizonte, Minas Gerais, Brazil.
Sidonia Barbara Guiomar EckleDepartment of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Jordana Grazziela Alves Coelho-Dos-ReisRené Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ-MINAS), Belo Horizonte, Minas Gerais, Brazil.
Vanessa Peruhype-MagalhãesRené Rachou Institute, Oswaldo Cruz Foundation (FIOCRUZ-MINAS), Belo Horizonte, Minas Gerais, Brazil.
Fundação Oswaldo Cruz · BRUniversity of Melbourne · AUFundação Hospitalar do Estado de Minas Gerais · BRUniversidade Federal de Minas Gerais · BRColumbia University · USPeter Doherty Institute · AU

Funding

Investigating the basis of MAIT cell antigen potencyR01AI148407 · NIAID · UNIVERSITY OF MELBOURNE · PI MCCLUSKEY, JAMES · 2020 to 2024
$2.7M
CD1d/NKT-binding glycolipids in enhancing the immunogenicity of a malaria vaccineR01AI070258 · NIAID · AARON DIAMOND AIDS RESEARCH CENTER · PI TSUJI, MORIYA · 2012 to 2016
$2.2M
NIAID NIH HHS R01 AI070258NIAID NIH HHS R01 AI148407
6 · The paper itself

Abstract

Mucosal-associated invariant T (MAIT) cells are restricted by MR1 and are known to protect against bacterial and viral infections. Our understanding of the role of MAIT cells in parasitic infections, such as visceral leishmaniasis (VL) caused by protozoan parasites of

Indexed as

Leishmaniasis, VisceralMucosal-Associated Invariant T CellsAlanine TransaminaseChildCytokinesHemoglobinsHumansInterleukin-10Interleukin-17Alanine TransaminaseCytokinesHemoglobinsInterleukin-10Interleukin-17anti-parasitic activityIFN-γ+ MAITIL-17+MAITLeishmaniaMAITMR1TNF+MAIT

Identifiers

PMID36189274
PMCPMC9521739
OpenAlexW4295950529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.