Evidence map›Paper›PMID 36189006›Full record

ArticleFrontiers in rehabilitation sciences2022

Exercise engagement drives changes in cognition and cardiorespiratory fitness after 8 weeks of aerobic training in sedentary aging adults at risk of cognitive decline.

Carrie A Hinchman, Danylo F Cabral, Marissa Ciesla, Marti Flothmann, Christina Nunez, Jordyn Rice, David A Loewenstein, Marcela Kitaigorodsky, Lawrence P Cahalin, Tatjana Rundek and 3 more

Abstract read
In one paragraph

Article in Frontiers in rehabilitation sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carrie A HinchmanSchool of Medicine, New York Medical College, Valhalla, NY, United States.
Danylo F CabralDepartment of Physical Therapy, University of Miami Miller School of Medicine, Coral Gables, FL, United States.
Marissa CieslaLinus Health, Waltham, MA, United States.
Marti FlothmannDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL, United States.
Christina NunezDepartment of Physical Therapy, University of Miami Miller School of Medicine, Coral Gables, FL, United States.
Jordyn RiceDepartment of Physical Therapy, University of Miami Miller School of Medicine, Coral Gables, FL, United States.
David A LoewensteinCenter for Cognitive Neuroscience and Aging, University of Miami Miller School of Medicine, Miami, FL, United States.
Marcela KitaigorodskyCenter for Cognitive Neuroscience and Aging, University of Miami Miller School of Medicine, Miami, FL, United States.
Lawrence P CahalinDepartment of Physical Therapy, University of Miami Miller School of Medicine, Coral Gables, FL, United States.
Tatjana RundekDepartment of Neurology, University of Miami Miller School of Medicine, Miami, FL, United States.
Alvaro Pascual-LeoneLinus Health, Waltham, MA, United States.
Gabriele CattaneoGuttmann Brain Health Institute, Barcelona, Spain.
Joyce Gomes-OsmanLinus Health, Waltham, MA, United States.

Funding

Institutional Career Development CoreKL2TR002737 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RUNDEK, TATJANA, SCOTT, GWENDOLYN BARBARA · 2018 to 2022
$3.6M
NCATS NIH HHS KL2 TR002737
6 · The paper itself

Abstract

Background: With our aging population, many individuals are at risk of developing age-related cognitive decline. Physical exercise has been demonstrated to enhance cognitive performance in aging adults. This study examined the effects of 8 weeks of aerobic exercise on cognitive performance and cardiorespiratory fitness in sedentary aging adults at risk for cognitive decline. Methods: Fifty-two participants (age 62.9 ± 6.8, 76.9% female) engaged in eight weeks of moderate-to high-intensity exercise (19 in-person, 33 remotely). Global cognition was measured by the Repeatable Battery for the Assessment of Neuropsychological Status, the Delis-Kaplan Executive Function System, and the Digit Span subtest of the Wechsler Adult Intelligence Scale (WAIS) Fourth Edition. Cardiorespiratory fitness was measured Results: Overall, 63.4 % of participants demonstrated high engagement (≥ 70% total exercise time spent in the prescribed heart rate zone). There were significant pre-post improvements in verbal fluency and verbal memory, and a significant decrement in working memory, but these were associated with small effect sizes (Cohen's d <0.5). Concerning cardiorespiratory fitness, there was a pre-to-post significant improvement in HRR1 ( Conclusion: Improvements in cognition and cardiorespiratory fitness were observed after 8 weeks of moderate to high-intensity exercise in aging adults. These results suggest that committing to a regular exercise regimen, even for a brief two-month period, can promote improvements in both cardiorespiratory fitness and cognitive performance, and that improvements are driven by exercise engagement.

Indexed as

aerobic exerciseaging adultscardiorespiratory fitnesscognitive enhancementexercise engagement

Identifiers

PMID36189006
PMCPMC9397848

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.