Evidence map›Paper›PMID 36188946›Full record

ArticleFrontiers in rehabilitation sciences2022

Multi-center, single-blind randomized controlled trial comparing functional electrical stimulation therapy to conventional therapy in incomplete tetraplegia.

Kim D Anderson, Radha Korupolu, Kristin E Musselman, Jacqueline Pierce, James R Wilson, Nuray Yozbatiran, Naaz Desai, Milos R Popovic, Lehana Thabane

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in rehabilitation sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03439319 (Restoration of Reaching and Grasping Function in Individuals With Spinal Cord Injury Using MyndMove® Neuromodulation Therapy), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03439319 nacompletednot on this map

Restoration of Reaching and Grasping Function in Individuals With Spinal Cord Injury Using MyndMove® Neuromodulation Therapy

TypeinterventionalSponsorMyndTec Inc.Ran2019 to 2022Enrolled51ConditionsSpinal Cord Injuries, Trauma, Nervous SystemArmsMyndMove®, Conventional Therapy
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Kim D AndersonMetroHealth Rehabilitation Institute, MetroHealth System, Cleveland, OH, United States.
Radha KorupoluDepartment of Physical Medicine and Rehabilitation, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States.
Kristin E MusselmanThe KITE Research Institute, University Health Network, Toronto, ON, Canada.
Jacqueline PierceHealthTech Connex Centre for Neurology Studies/Neuromotion Physiotherapy, Vancouver, BC, Canada.
James R WilsonMetroHealth Rehabilitation Institute, MetroHealth System, Cleveland, OH, United States.
Nuray YozbatiranDepartment of Physical Medicine and Rehabilitation, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, United States.
Naaz DesaiKrembil Research Institute-University Health Network, Toronto, ON, Canada.
Milos R PopovicThe KITE Research Institute, University Health Network, Toronto, ON, Canada.
Lehana ThabaneDepartment of Health Research Methods, Evidence, and Impact, Faculty of Health Sciences, McMaster University, Hamilton ON, Canada.
University Health Network · CAMcMaster University · CAMemorial Hermann Institute for Rehabilitation and Research Foundation · USMetroHealth · USThe University of Texas Health Science Center at Houston · USUniversity School · US

Funding

Institutional Career Development CoreKL2TR003168 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MILLER, CHARLES C · 2019 to 2023
$4.9M
Advanced Platform Technology Center of ExcellenceI50RX001871 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI MARGOT S. DAMASER, Gilles Pinault · 2015 to 2026
–
NCATS NIH HHS KL2 TR003168RRD VA I50 RX001871
6 · The paper itself

Abstract

Background: Loss of upper extremity function after tetraplegia results in significant disability. Emerging evidence from pilot studies suggests that functional electrical stimulation (FES) therapy may enhance recovery of upper extremity function after tetraplegia. The aim of this trial was to determine the effectiveness of FES therapy delivered by the Myndmove stimulator in people with tetraplegia. Methods: A multi-center Results: Between June 2019 to August 2021, 51 participants were randomized to FES ( Conclusion: Forty sessions of FES therapy delivered by the MyndMove stimulator are as effective as conventional therapy in producing meaningful functional improvements that persist after therapy is completed. Limitations of this study include the impact of COVID-19 limiting the ability to recruit the target sample size and per-protocol execution of the study in one-third of the participants. Registration: This trial is registered at www.ClinicalTrials.gov, NCT03439319.

Indexed as

functional electrical simulation (FES)rehabilationspinal cord injurytetraplegiatherapy

Identifiers

PMID36188946
PMCPMC9500231
OpenAlexW4295183071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.