Evidence map›Paper›PMID 36188619›Full record

ReviewFrontiers in pharmacology2022

Control of aging by the renin-angiotensin system: a review of

Brian M Egan, Andrea Scharf, Franziska Pohl, Kerry Kornfeld

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Cardioprotective Role of Captopril: From Basic to Applied Investigations.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Review
  9. Inhibition ofmicroPublication biology · 2025
    Article
  10. Review
  11. Article
  12. Genome-Wide Analysis ofInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Brian M EganDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, MO, United States.
Andrea ScharfDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, MO, United States.
Franziska PohlDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, MO, United States.
Kerry KornfeldDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, MO, United States.
Washington University in St. Louis · US

Funding

DISCOVER DETERMINANTS OF INDIVIDUAL LIFESPAN AND HEALTHR01AG057748 · NIA · WASHINGTON UNIVERSITY · PI KORNFELD, KERRY · 2019 to 2023
$2.1M
NIA NIH HHS R01 AG057748
6 · The paper itself

Abstract

The free-living, non-parasitic nematode

Indexed as

ACE-angiotensin-converting enzymeacn-1AnceCaptopril (ACE-I)EnalaprilLisinoprillongevityLosartan

Identifiers

PMID36188619
PMCPMC9518657
OpenAlexW4295682182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.