Evidence map›Paper›PMID 36188602›Full record

ArticleFrontiers in pharmacology2022

Apamin structure and pharmacology revisited.

Alexey I Kuzmenkov, Steve Peigneur, Joshua A Nasburg, Konstantin S Mineev, Maxim V Nikolaev, Ernesto Lopes Pinheiro-Junior, Alexander S Arseniev, Heike Wulff, Jan Tytgat, Alexander A Vassilevski

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Exploratory proteomic characterization ofFrontiers in pharmacology · 2026
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  8. Therapeutic Bioactivity Exerted by theMolecules (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Activation of Small Conductance CaInternational journal of molecular sciences · 2025
    Article
  13. Article
  14. Article
  15. The Anti-Leukemic Potential of Bee Venom.International journal of general medicine · 2025
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Alexey I KuzmenkovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Steve PeigneurToxicology and Pharmacology, KU Leuven, Leuven, Belgium.
Joshua A NasburgDepartment of Pharmacology, University of California, Davis, Davis, CA, United States.
Konstantin S MineevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Maxim V NikolaevSechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, Saint Petersburg, Russia.
Ernesto Lopes Pinheiro-JuniorToxicology and Pharmacology, KU Leuven, Leuven, Belgium.
Alexander S ArsenievShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Heike WulffDepartment of Pharmacology, University of California, Davis, Davis, CA, United States.
Jan TytgatToxicology and Pharmacology, KU Leuven, Leuven, Belgium.
Alexander A VassilevskiShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
KU Leuven · BEInstitute of Bioorganic Chemistry · RUMoscow Institute of Physics and Technology · RUUniversity of California, Davis · USInstitute of Evolutionary Physiology and Biochemistry · RU

Funding

Predoctoral Training in Pharmacological SciencesT32GM099608 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2012 to 2021
$2.2M
NIGMS NIH HHS T32 GM099608
6 · The paper itself

Abstract

Apamin is often cited as one of the few substances selectively acting on small-conductance Ca

Indexed as

apaminApis melliferabee venomcalcium-activated potassium channelion channelspatial structure

Identifiers

PMID36188602
PMCPMC9523135
OpenAlexW4296168543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.