Evidence map›Paper›PMID 36188489›Full record

ArticleAging and cancer2022

Cancer and aging: A call to action.

Dejana Braithwaite, Stephen Anton, Supriya Mohile, James DeGregori, Nancy Gillis, Daohong Zhou, Shirley Bloodworth, Marco Pahor, Jonathan Licht

Open access · goldAbstract read
In one paragraph

Article in Aging and cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 1 country.

Dejana BraithwaiteDepartments of Surgery and Epidemiology, University of Florida, Gainesville, Florida, USA.
Stephen AntonUniversity of Florida Health Cancer Center, University of Florida, Gainesville, Florida, USA.
Supriya MohileDepartment of Medicine, University of Rochester Medical Center, Rochester, New York, USA.
James DeGregoriDepartment of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado, USA.
Nancy GillisDepartment of Cancer Epidemiology and Malignant Hematology, Moffitt Cancer Center, Tampa, Florida, USA.
Daohong ZhouDepartment of Biochemistry and Structural Biology, University of Texas Health Sciences Center at San Antonio, San Antonio, Texas, USA.
Shirley BloodworthUniversity of Florida Health Cancer Center, University of Florida, Gainesville, Florida, USA.
Marco PahorInstitute on Aging, University of Florida, Gainesville, Florida, USA.
Jonathan LichtUniversity of Florida Health Cancer Center, University of Florida, Gainesville, Florida, USA.
University of Florida Health · USInstitute on Aging · USMoffitt Cancer Center · USThe University of Texas at San Antonio · USUF Health Cancer CenterUniversity of Colorado Denver · USUniversity of Florida · USUniversity of Rochester Medical Center · US

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
Personalized screening for lung cancer: the importance of co-existing chronic conditions to clinical practice and policyR01CA249506 · NCI · UNIVERSITY OF FLORIDA · PI BRAITHWAITE, DEJANA K, GOULD, MICHAEL K · 2020 to 2025
$3.3M
Aged tissue environments as drivers of oncogenic adaptation in hematopoiesisR01AG066544 · NIA · UNIVERSITY OF COLORADO DENVER · PI DEGREGORI, JAMES V · 2020 to 2024
$1.1M
NCI NIH HHS R01 CA249506NIA NIH HHS P30 AG028740NIA NIH HHS R01 AG066544
6 · The paper itself

Abstract

Background: The intersection of cancer and aging is an emerging public health challenge in developed countries because of the aging and expansion of the population. Aims: We convened a panel of experts to share their insights on this topic at the inaugural University of Florida Health Cancer Center's (UFHCC's) Cancer and Aging Symposium, which was held virtually in February 2022. Methods: We featured presentations from four leading scientists, whose research spans multiple disciplines including basic science, translational research, geriatric oncology, and population science. Results: Each speaker offered their unique perspective and insight on the intersection between cancer and aging and discussed their current and ongoing research in this field. In addition to this panel of experts, scientists from the National Institutes of Health and the National Cancer Institute, as well as a UFHCC-affiliated citizen scientist, shared their perspectives on strategies to move the field forward. Some of the key open questions and opportunities for future research offered by these presenters in aging and cancer include but are not limited to infusing health disparities research into the field of cancer and aging, assessing the value of geriatric assessment in identifying early vulnerabilities that may affect response to emerging cancer therapies in older patients, and assessing biological age and other biomarkers (e.g., clonal hematopoiesis) in relation to clinical endpoints and the development of primary, secondary, and tertiary cancer prevention interventions. Conclusion: Research is needed to accelerate knowledge regarding the dynamic interplay of cancer and aging and optimize care in diverse older adults to achieve equity in cancer outcomes.

Indexed as

agingcancertransdisciplinary science

Identifiers

PMID36188489
PMCPMC9521708
OpenAlexW4285395942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.