SynthesisFrontiers in neurology2022
Epidemiology of intracerebral hemorrhage: A systematic review and meta-analysis.
Synthesis in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The APOE paradox: divergent genetic influences on hemorrhagic stroke risk-A meta-analysis.Frontiers in stroke · 2026Pooled it
- Cerebral Small-Vessel Disease Markers on Magnetic Resonance Imaging as Predictors of Recurrent Vascular Events and Death in Ischemic Stroke: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2025Pooled it
- Inflammatory bowel disease and the risk of intracerebral hemorrhage: A Mendelian randomization study and meta-analysis.Immunity, inflammation and disease · 2023Pooled it
- Neutrophil-to-lymphocyte ratio, white blood cell, and C-reactive protein predicts poor outcome and increased mortality in intracerebral hemorrhage patients: a meta-analysis.Frontiers in neurology · 2023Pooled it
- Prophylactic Antiepileptic Drugs in Nontraumatic Intracerebral Hemorrhage: A Network Meta-Analysis.Neurocritical care · 2026Article
- Atypical Intracerebral Hemorrhage With a Fatal Outcome Following the ChAdOx1 nCoV-19 Vaccine.Cureus · 2026Article
- Incidence, clinical characteristics and outcome of spontaneous cerebellar intracerebral haemorrhage in a Norwegian population.European stroke journal · 2026Article
- In-hospital case-fatality after intracerebral hemorrhage in southern Iran: a single-center retrospective study.BMC neurology · 2026Observational
- Temporal Increase in Strict Spontaneous Intracerebral Hemorrhage Admissions During the First March Following Direct Israel-Iran Hostilities: Preliminary Single-Center Findings from a Decade-Referenced Neuroscience Services Cohort.International journal of environmental research and public health · 2026Observational
- A Low LDL-C Level but not Statin Use is Associated with In-hospital Mortality in Spontaneous Intracerebral Hemorrhage; The J-ICH Registry.Journal of atherosclerosis and thrombosis · 2026Article
- Andexanet Alfa for Life-Threatening Bleeding Following Factor Xa Inhibitor Treatment: Postmarketing Surveillance Study in Japan.JACC. Asia · 2026Article
- Spontaneous atraumatic pediatric basal ganglia hemorrhage in the setting of COLGALT1-related collagenopathy: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Brain intraparenchymal hemorrhage following urgent cesarean section: a case report.Journal of medical case reports · 2026Article
- Incidence and Prognostic Indicators of Dementia in Patients With Covert Brain Infarction, Transient Ischemic Attack, and Stroke: The Population-Based Rotterdam Study.Journal of the American Heart Association · 2026Article
- Morphological vessel analysis of intracranial basal ganglia hemorrhage on computed tomography angiography image.BMC neurology · 2026Article
- Association of platelet to HDL-C ratio with short-term mortality in critically ill intracerebral hemorrhage patients: a MIMIC-IV analysis.Scientific reports · 2026Article
- Pre-Hospital Rate-Pressure Product Is Not Positively Associated with Hematoma Expansion or Initial Hematoma Volume in Spontaneous Intracranial Hemorrhage.Neurology international · 2026Article
- Efficacy of pregabalin in the treatment of acute cerebral hemorrhage and its influence on prognosis.Frontiers in pharmacology · 2026Article
- Article
- Acupuncture at "Baihui" and "Xuanli" attenuates intracerebral hemorrhage-induced brain injury by modulating autophagy and the PI3K/AKT signaling pathway in rats.American journal of translational research · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Intracerebral hemorrhage (ICH) is associated with high mortality and disability rates. This study aimed to investigate the relationship between sex, age, study year, risk factors, bleeding site, median year of study, and the incidence of ICH. Method: Literature on the incidence of ICH published on 1 January 1980 and 1 January 2020, was systematically retrieved from PubMed and Embase databases. The random-effects model and subgroup analysis were used to explore the relationship between the incidence of ICH and different ages, sex, bleeding sites, and risk factors. Results: We summarized the epidemiological changes in ICH in the past 40 years according to 52 studies and found that the total incidence of ICH is 29.9 per 100,000 person-years (95% CI: 26.5-33.3), which has not decreased worldwide. The incidence of ICH in the Asian population is much higher than in other continents. In addition, the incidence of ICH increases with age and differs at the 85-year-old boundary. Men are more likely to develop ICH than women, and the basal ganglia region is the most common area for ICH. Of the 10 risk factors examined in this study, those with hypertension had the highest incidence of ICH, followed by those with excessive alcohol consumption and heart disease. Conclusion: The prevention and treatment of ICH still need to be improved continuously according to age, sex, risk factors, and other factors, and targeted and normative strategies should be gradually developed in the future.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.