Evidence map›Paper›PMID 36188358›Full record

ArticleFrontiers in neurology2022

Predictors of futile recanalization in patients with acute ischemic stroke undergoing mechanical thrombectomy in late time windows.

Heng Ni, Xinglong Liu, Yu Hang, Zhenyu Jia, Yuezhou Cao, Haibin Shi, Sheng Liu, Linbo Zhao

Abstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Heng NiDepartment of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xinglong LiuDepartment of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yu HangDepartment of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zhenyu JiaDepartment of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yuezhou CaoDepartment of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Haibin ShiDepartment of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Sheng LiuDepartment of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Linbo ZhaoDepartment of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Futile recanalization (FR), defined as functional dependence despite successful reperfusion, is common in patients who experience an acute stroke after thrombectomy. We aimed to determine the predictors of FR in patients who underwent thrombectomy in late time windows (6 h or more after symptom onset). Methods: This retrospective review included patients who underwent thrombectomy for acute anterior circulation large vessel occlusion from October 2019 to June 2021. Successful reperfusion was defined as a modified Thrombolysis in Cerebral Infarction (mTICI) score of 2b/3. Functional dependence at 90 days was defined as a modified Rankin scale score of 3-6. Multivariate analysis and a receiver operating characteristic (ROC) curve were used to identify the predictors of FR in patients treated in delayed time windows. Results: Of the 99 patients included, FR was observed in 51 (51.5%). In the multivariate analysis, older age (OR, 1.12; 95% CI, 1.04-1.22; Conclusions: Older age, female sex, higher NIHSS score upon admission, and an increased number of passes per procedure were independent predictors of FR in patients who experienced acute ischemic strokes after thrombectomy in late time windows.

Indexed as

acute ischemic strokefutile recanalizationlate time windowsmechanical thrombectomypredictors

Identifiers

PMID36188358
PMCPMC9519892

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.