ArticleFrontiers in microbiology2022
Metabolome, microbiome, and gene expression alterations in the colon of newborn piglets with intrauterine growth restriction.
Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Linking the degree of intrauterine growth restriction to alterations in metabolism, energy reserves, and gut health in newborn piglets.Journal of animal science · 2026Article
- Unraveling the persistent renal impact of intrauterine growth restriction and catch-up growth: integrating morphological insights with metabolomic profiling.Journal of molecular histology · 2025Article
- Connecting Molecular Characteristics of Intrauterine Growth-Retarded Piglets to Targeted Nutritional Interventions: A Review.Animals : an open access journal from MDPI · 2025Review
- Dietary Supplementation with Fermented Milk Improves Growth Performance and Intestinal Functions in Intrauterine Growth-Restricted Piglets.Animals : an open access journal from MDPI · 2025Article
- Targeting Catenibacterium mitsuokai with icariin modulates gut microbiota and improves hepatic lipid metabolism in intrauterine growth restriction.The ISME journal · 2025Article
- Disrupted Microbiota of Colon Results in Worse Immunity and Metabolism in Low-Birth-Weight Jinhua Newborn Piglets.Microorganisms · 2024Article
- Phosphatidylethanolamine Improves Postnatal Growth Retardation by Regulating Mucus Secretion of Intestinal Goblet Cells in Piglets.Animals : an open access journal from MDPI · 2024Article
- Intrauterine Growth Restriction Affects Colonic Barrier FunctionAntioxidants (Basel, Switzerland) · 2024Article
- Metabolic and fecal microbial changes in adult fetal growth restricted mice.Pediatric research · 2024Article
- Calorie restriction during gestation impacts maternal and offspring fecal microbiome in mice.Frontiers in endocrinology · 2024Article
- Intrauterine growth restriction alters kidney metabolism at the end of nephrogenesis.Nutrition & metabolism · 2023Article
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Authors and funding
6 authors.
Funding
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Abstract
Newborn animals with intrauterine growth restriction (IUGR) are characterized by impaired intestinal structure and function; however, their intestinal microbiota and metabolome profiles have not been fully identified. The present study investigated the differences in colonic microbiota, metabolomics, and barrier function-related gene expression profiles between the IUGR and normal birth weight (NBW) piglets at 7, 21, and 28 days of age. Forty-eight piglets (24 NBW and 24 IUGR) from 24 litters were assigned to assess the differences in colonic microbiota, metabolomics, and gene expression between IUGR and NBW piglets. Compared with the NBW piglets, IUGR piglets showed decreased Shannon index and increased Simpson index at 7 days of age and Chao1 index at 21 days of age (
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