ArticleJournal of conservative dentistry : JCD
The effect of chitosan nanoparticle, citric acid, and ethylenediaminetetraacetic acid on dentin smear layer using two different irrigation needles: A scanning electron microscope study.
Article in Journal of conservative dentistry : JCD. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Chitosan's Ability to Remove the Smear Layer-A Systematic Review of Ex Vivo Studies.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Smear layer removal and antimicrobial efficacy of chitosan as a root canal irrigant: a systematic review of in-vitro studies.Odontology · 2025Pooled it
- Comparative evaluation of chitosan nanoparticles and ethylenediaminetetraacetic acid as intracanal irrigants and their effect on postoperative pain reduction in single-sitting root canal treatment - A randomized controlled trial.Journal of conservative dentistry and endodontics · 2026Article
- The efficacy of different irrigant activation methods in the elimination of bacteria colonizing in dentin tubules.European oral research · 2026Article
- Is continuous soft chelation protocol more efficacious than conventional irrigation protocol in removing the smear layer? - A systematic review.Journal of conservative dentistry and endodontics · 2026Review
- Effect of Apical Preparation Size and Preparation Taper on Smear Layer Removal Using Two Different Irrigation Needles: A Scanning Electron Microscopy Study.European journal of dentistry · 2025Article
- Article
- Effectiveness of Triton Irrigation Solution in Smear Layer Removal: An in-vitro Study.European endodontic journal · 2024Article
- Application of Nanomaterials in Endodontics.BME frontiers · 2024Review
- Comparative evaluation of antifungal efficacy of conventional endodontic irrigants and chitosan nanoparticles.Journal of conservative dentistry : JCDArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: The objective of this study is to compare the efficacy of chitosan (CS) nanoparticles (CNPs), citric acid (CA), and ethylenediaminetetraacetic acid (EDTA) in removing the smear layer using two different irrigation needles. Materials and Methods: Palatal roots of 70 maxillary first molars were decoronated, instrumented, and divided into four experimental groups ( Statistical Analysis Used: Nonparametric Kruskal-Wallis and Mann-Whitney Results: CNPs were as efficient as CA and EDTA as a chelating agent. However, significantly more efficient apically. At all three levels, there was no significant difference between A1 and A2. At the coronal and middle levels, there was a significant difference between B1 and B2, as well as apically between C1 and C2. Conclusions: CNPs remove the smear layer with the same efficiency as other irrigants utilized in this study at coronal and middle levels and more efficiently at the apical levels. IrriFlex
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.