ArticleFrontiers in veterinary science2022
Epidemiological survey of PRRS and genetic variation analysis of the ORF5 gene in Shandong Province, 2020-2021.
Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed.
- Immunogenicity of an Oil-in-Water Emulsion ContainingVaccines · 2026Article
- Analysis of Molecular Epidemiological Characteristics of Porcine Reproductive and Respiratory Syndrome Virus Type 2 in Shandong Province from 2023 to 2025.Veterinary sciences · 2026Article
- Epidemiological analysis based on ORF5 of porcine reproductive and respiratory syndrome virus in China in 2019-2024.Frontiers in microbiology · 2026Article
- Molecular epidemiology and genetic evolution of PRRSV ORF5 in Sichuan, Southwest China.Frontiers in microbiology · 2026Article
- Molecular Epidemiology and Genetic Evolution Analysis of Porcine Reproductive and Respiratory Syndrome Virus in Southern Xinjiang, China, from 2023 to 2025.Veterinary sciences · 2025Article
- Etiological Detection, Isolation, and Pathogenicity of Porcine Reproductive and Respiratory Syndrome Virus in China.Veterinary sciences · 2025Article
- Genetic variation in NSP4 of type 1 porcine reproductive and respiratory syndrome virus in China.BMC veterinary research · 2025Article
- Genetic evolution analysis of PRRSV ORF5 gene in five provinces of Northern China in 2024.BMC veterinary research · 2025Article
- Prevalence and genetic diversity ofFrontiers in veterinary science · 2025Article
- Development of SYBR green I-based real-time qPCR differential diagnosis assays for porcine reproductive and respiratory syndrome virus typing in Guangdong province.Frontiers in veterinary science · 2025Article
- Antiviral effects and mechanism of Ma-Xing-Shi-Gan-San on porcine reproductive and respiratory syndrome virus.Frontiers in microbiology · 2025Article
- Epidemiology and genetic characterization of porcine reproductive and respiratory syndrome virus in Fujian Province, China, from 2023 to 2024.Frontiers in veterinary science · 2025Article
- Isolation and pathogenicity comparison of two novel natural recombinant porcine reproductive and respiratory syndrome viruses with different recombination patterns in Southwest China.Microbiology spectrum · 2024Article
- Spatiotemporal Distribution of PRRSV-1 Clades in Hungary with a Focus on the Era of Disease Eradication.Animals : an open access journal from MDPI · 2024Article
- Efficacy of a reduced-dosage PRRS MLV vaccine against a NADC34-like strain of porcine reproductive and respiratory syndrome virus.Frontiers in veterinary science · 2024Article
- Evaluation of cross-protection of a reduced-dose PRRS MLV vaccine against the NADC30-like PRRSV challenge.Frontiers in veterinary science · 2024Article
- Article
- Research Progress on Glycoprotein 5 of Porcine Reproductive and Respiratory Syndrome Virus.Animals : an open access journal from MDPI · 2023Review
- Genetic variation and recombination analysis of theFrontiers in microbiology · 2023Article
- Classification of porcine reproductive and respiratory syndrome clinical impact in Ontario sow herds using machine learning approaches.Frontiers in veterinary science · 2023Article
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10 authors.
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Abstract
Since the rise of porcine reproductive and respiratory syndrome virus (PRRSV) in China, mutations have occurred regularly. In particular, the emergence of HP-PRRSV has significantly improved the pathogenicity of PRRSV. It has brought huge economic losses to the Chinese pig farming industry. To understand the current prevalence and evolution of PRRSV in Shandong Province, 1,344 samples suspected of having PRRSV were collected from local hog farms of different sizes. Genetic variation in the isolated PRRSV ORF5 gene was analyzed using the RT-PCR method. The results showed that the detection rate of PRRSV in the collected samples was 25.44%. The predominant strain of PRRSV in Shandong Province is still NADC30-like. However, it cannot be ignored that NADC34-like is also starting to become a prevalent strain. Mutations in ORF5 amino acids 13, 151 and neutralizing epitope (aa36-aa52) in some isolates can cause changes in virulence and ability to escape immunity. This study enriches the epidemiological data on PRRSV in Shandong Province, China. It provides an important reference for the development of new vaccines and for the prevention and control of PRRSV.
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