Evidence map›Paper›PMID 36187805›Full record

ArticleFrontiers in veterinary science2022

Positive effects of Mulberry leaf extract on egg quality, lipid metabolism, serum biochemistry, and antioxidant indices of laying hens.

Bo Zhang, Zeben Wang, Chenxuan Huang, Dehe Wang, Dongmei Chang, Xiaowei Shi, Yifan Chen, Hui Chen

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Nutritional and Functional Effects ofAnimals : an open access journal from MDPI · 2026
    Article
  2. Article
  3. Article
  4. Dietary Supplementation withVeterinary sciences · 2026
    Article
  5. Article
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  7. Article
  8. Article
  9. Article
  10. Article
  11. Purple corn cob (Journal of advanced veterinary and animal research · 2025
    Article
  12. Tartary Buckwheat Flavonoids and 25-Hydroxyvitamin DAnimals : an open access journal from MDPI · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Effects ofFrontiers in veterinary science · 2025
    Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bo ZhangCollege of Animal Science and Technology, Hebei Agricultural University, Baoding, China.
Zeben WangCollege of Management Science and Engineering, Hebei University of Economics and Business, Shijiazhuang, China.
Chenxuan HuangCollege of Animal Science and Technology, Hebei Agricultural University, Baoding, China.
Dehe WangCollege of Animal Science and Technology, Hebei Agricultural University, Baoding, China.
Dongmei ChangZhengding County Mulberry Industry Application Research Institute, Shijiazhuang, China.
Xiaowei ShiZhengding County Mulberry Industry Application Research Institute, Shijiazhuang, China.
Yifan ChenCollege of Animal Science and Technology, Hebei Agricultural University, Baoding, China.
Hui ChenCollege of Animal Science and Technology, Hebei Agricultural University, Baoding, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant extracts are becoming a hot topic of research by animal husbandry practitioners following the implementation of a global policy to restrict antibiotic use in animal production. Mulberry leaf extract has received considerable attention as a new plant extract. Mulberry leaf polysaccharides and flavonoids are its main constituents, and these substances possess immunoregulatory, hypoglycemic, antioxidant, and anticoagulant properties. It is however less common to use them in poultry production. Therefore, we investigated the effects of adding MLE to the diet of laying hens on egg quality, lipid metabolism, serum biochemistry, and antioxidant indices in this study. A total of 288 Lohmann Silber layers, aged 38 weeks, were randomly assigned to four groups (six replicates of 12 hens each). Hens were fed a basal diet supplemented with 0 (control diet), 0.4, 0.8, or 1.2% MLE for 56 d. Results showed that the addition of 0.4-1.2% MLE to the diet improved aspartate transaminase (AST) activity in the serum of laying hens, reduced low-density lipoprotein (LDL-C) content in the serum, and significantly decreased yolk triglyceride (TG) and total cholesterol (TC) contents (

Indexed as

antioxidant indexesegg qualitylaying henlipid metabolismmulberry leaf extract (MLE)

Identifiers

PMID36187805
PMCPMC9523877

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.