Evidence map›Paper›PMID 36187760›Full record

ArticleFrontiers in physiology2022

Mitochondrial-targeted antioxidant supplementation for improving age-related vascular dysfunction in humans: A study protocol.

Kevin O Murray, Morgan Berryman-Maciel, Sanna Darvish, McKinley E Coppock, Zhiying You, Michel Chonchol, Douglas R Seals, Matthew J Rossman

Abstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Mitochondria-Targeting Moieties Based on N-Tethered Pyridinium Cations.Angewandte Chemie (International ed. in English) · 2026
    Article
  5. Review
  6. Proteome-wide association study of cortical proteins that may provide resilience for late-life disability.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  7. Review
  8. Review
  9. Review
  10. HYQTD Drug-containing Serum Alleviates HCurrent pharmaceutical biotechnology · 2026
    Article
  11. Mitochondria as a Therapeutic Target in Metabolic Disorders.Mini reviews in medicinal chemistry · 2026
    Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Oxidative Stress in Cardiovascular Diseases: Mechanisms and Exploring Advanced Therapies.Cardiovascular & hematological agents in medicinal chemistry · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kevin O MurrayIntegrative Physiology of Aging Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States.
Morgan Berryman-MacielIntegrative Physiology of Aging Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States.
Sanna DarvishIntegrative Physiology of Aging Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States.
McKinley E CoppockIntegrative Physiology of Aging Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States.
Zhiying YouDivision of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Michel ChoncholDivision of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Douglas R SealsIntegrative Physiology of Aging Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States.
Matthew J RossmanIntegrative Physiology of Aging Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States.

Funding

Mitochondrial-targeted antioxidant supplementation for improving vascular endothelial function inpostmenopausal women: comparison with standard-of-care exerciseR01AG066730 · NIA · UNIVERSITY OF COLORADO · PI Matthew J Rossman, DOUGLAS R SEALS · 2021 to 2026
$4.0M
NIA NIH HHS R01 AG066730
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

agingarterial stiffnessendothelial functionmitochondriareactive oxgen species

Identifiers

PMID36187760
PMCPMC9520456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.