ReviewWorld journal of nephrology2022
Management and outcomes of acute post-streptococcal glomerulonephritis in children.
Review in World journal of nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Coexistence of acute post-streptococcal glomerulonephritis and acute rheumatic fever: case report and systematic review.Pediatric nephrology (Berlin, Germany) · 2026Pooled it
- Cardiac changes in children with post-streptococcal glomerulonephritis: a prospective observational study.BMC pediatrics · 2026Observational
- C-reactive protein as a potential effector molecule in the pathogenesis of acute post-streptococcal glomerulonephritis: a narrative review.Pediatric nephrology (Berlin, Germany) · 2026Review
- Epidemiology and Clinical Characteristics of Pediatric Acute Postinfectious Glomerulonephritis in Montenegro: A Nationwide Retrospective Study.Balkan medical journal · 2026Article
- Outcomes and Predictors of Acute Post-Streptococcal Glomerulonephritis in Hospitalized Children in Northwest Ethiopia: A Multicenter Retrospective Cohort Study.Health science reports · 2026Article
- Exploring the global, regional, and Chinese disease burden of acute glomerulonephritis from 1990 to 2021 and future trends up to 2039 based on the 2021 Global Burden of Disease Database.International urology and nephrology · 2026Article
- Post-streptococcal glomerulonephritis in Xakriabá indigenous children: case reports.CEN case reports · 2026Article
- Analysis of acute glomerulonephritis disease burden and incidence trends in China, 1990-2021.International urology and nephrology · 2026Article
- Infective Endocarditis-Associated Glomerulonephritis Caused byKidney & blood pressure research · 2026Article
- Case Report: A classical PSGN case with unusually prominent serosal manifestations and complement patterns that mimicked systemic autoimmune disease-highlighting diagnostic pitfalls and biopsy decision-making.Frontiers in pediatrics · 2026Article
- Article
- Patterns of Glomerular Injury: Histopathological Classification and Clinical Correlation.Cureus · 2025Review
- A narrative review of acute post-streptococcal glomerulonephritis in Nepali children.BMC nephrology · 2025Review
- Post-streptococcal acute glomerulonephritis in children: Association between proteinuria levels and renal outcomes.World journal of clinical pediatrics · 2025Article
- Percutaneous Ultrasound-Guided Renal Biopsy in Greek Children: 15 Years of Experience at a Single Center.Pediatric reports · 2024Article
- Clinical Characteristics of Children with Acute Post-Streptococcal Glomerulonephritis and Re-Evaluation of Patients with Artificial Intelligence.Medeniyet medical journal · 2024Article
- Biomarkers of histologic severity in children with severe or atypical acute post-streptococcal glomerulonephritis.Pediatric nephrology (Berlin, Germany) · 2024Article
- Angiotensin II and post-streptococcal glomerulonephritis.Clinical and experimental nephrology · 2024Review
- Acute Post-streptococcal Glomerulonephritis in a Pediatric Population: A Five-Year Retrospective Study.Cureus · 2024Article
- Group A β-hemolytic Streptococcal Pharyngitis: An Updated Review.Current pediatric reviews · 2024Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute post-streptococcal glomerulonephritis (APSGN) is the major cause of acute glomerulonephritis among children, especially in low- and middle-income countries. APSGN commonly occurs following pharyngitis due to the activation of antibodies and complements proteins against streptococcal antigens through the immune-complex-mediated mechanism. APSGN can be presented as acute nephritic syndrome, nephrotic syndrome, and rapidly progressive glomerulonephritis, or it may be subclinical. The management of APSGN is mainly supportive in nature with fluid restriction, anti-hypertensives, diuretics, and renal replacement therapy with dialysis, when necessary, as the disease is self-limiting. Congestive heart failure, pulmonary edema, and severe hypertension-induced encephalopathy might occur during the acute phase of APSGN due to hypervolemia. APSGN generally has a favorable prognosis with only a small percentage of patients with persistent urinary abnormalities, persistent hypertension, and chronic kidney disease after the acute episode of APSGN. Decreased complement levels, increased C-reactive protein, and hypoalbuminemia are associated with disease severity. Crescent formations on renal biopsy and renal insufficiency on presentation may be the predictors of disease severity and poor outcomes in APSGN in children.
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