ArticleWorld journal of cardiology2022
Association of electrocardiographic markers with myocardial fibrosis as assessed by cardiac magnetic resonance in different clinical settings.
Article in World journal of cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Associating electrocardiographic abnormalities with coronary artery disease: insights into microvascular dysfunction from dynamic CT perfusion.European radiology · 2025Article
- Observational
- High-frequency content within the QRS complex can predict ventricular tachyarrhythmias in hypertrophic cardiomyopathy.Journal of arrhythmia · 2025Article
- Fragmented QRS, Arrhythmic Causes, and Myocardial Fibrosis Burden by Autopsy Among Countywide Sudden Deaths.Circulation. Arrhythmia and electrophysiology · 2025Article
- Enhancing risk stratification post-myocardial infarction: prognostic value of NT-proBNP and fQRS.Biomarkers in medicine · 2025Article
- Apelinergic System Affects Electrocardiographic Abnormalities Induced by Doxorubicin.Biomedicines · 2025Article
- The Role of Machine Learning in the Detection of Cardiac Fibrosis in Electrocardiograms: Scoping Review.JMIR cardio · 2024Article
- A Cautionary Tale of Hypertrophic Cardiomyopathy-From "Benign" Left Ventricular Hypertrophy to Stroke, Atrial Fibrillation, and Molecular Genetic Diagnostics: A Case Report and Review of Literature.International journal of molecular sciences · 2024Review
- Fragmentation of the QRS Complex Is Associated with Right Ventricular Dilatation and Mortality in Critically Unwell Coronavirus Disease 2019 Patients.Anatolian journal of cardiology · 2024Article
- Prevalence of electrocardiographic markers associated with myocardial fibrosis in masters athletes: a cohort study.BMJ open sport & exercise medicine · 2024Article
- Evaluation and Management of Sudden Death Risk in Repaired Tetralogy of Fallot.Journal of personalized medicine · 2023Review
- Editorial: Novel phenotyping and risk stratification strategies for heart failure.Frontiers in cardiovascular medicine · 2022Article
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11 authors.
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Abstract
backgroundCardiac magnetic resonance (CMR) is a unique tool for non-invasive tissue characterization, especially for identifying fibrosis.
aimTo present the existing data regarding the association of electrocardiographic (ECG) markers with myocardial fibrosis identified by CMR - late gadolinium enhancement (LGE).
methodsA systematic search was performed for identifying the relevant studies in Medline and Cochrane databases through February 2021. In addition, we conducted a relevant search by
resultsA total of 32 studies were included. In hypertrophic cardiomyopathy (HCM), fragmented QRS (fQRS) is related to the presence and extent of myocardial fibrosis. fQRS and abnormal Q waves are associated with LGE in ischemic cardiomyopathy patients, while fQRS has also been related to fibrosis in myocarditis. Selvester score, abnormal Q waves, and notched QRS have also been associated with LGE. Repolarization abnormalities as reflected by increased Tp-Te, negative T-waves, and higher QT dispersion are related to myocardial fibrosis in HCM patients. In patients with Duchenne muscular dystrophy, a significant correlation between fQRS and the amount of myocardial fibrosis as assessed by LGE-CMR was observed. In atrial fibrillation patients, advanced inter-atrial block is defined as P-wave duration ≥ 120 ms, and biphasic morphology in inferior leads is related to left atrial fibrosis.
conclusionMyocardial fibrosis, a reliable marker of prognosis in a broad spectrum of cardiovascular diseases, can be easily understood with an easily applicable ECG. However, more data is needed on a specific disease basis to study the association of ECG markers and myocardial fibrosis as depicted by CMR.
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