Evidence map›Paper›PMID 36187389›Full record

ArticleWorld journal of gastrointestinal oncology2022

Percutaneous insertion of a novel dedicated metal stent to treat malignant hilar biliary obstruction.

Francesco Cortese, Fabrizio Acquafredda, Andrea Mardighian, Maria Teresa Zurlo, Valentina Ferraro, Riccardo Memeo, Stavros Spiliopoulos, Riccardo Inchingolo

Abstract read
In one paragraph

Article in World journal of gastrointestinal oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Francesco CorteseInterventional Radiology Unit, Miulli Hospital, Acquaviva Delle Fonti 70124, Italy.
Fabrizio AcquafreddaInterventional Radiology Unit, Miulli Hospital, Acquaviva Delle Fonti 70124, Italy.
Andrea MardighianInterventional Radiology Unit, Miulli Hospital, Acquaviva Delle Fonti 70124, Italy.
Maria Teresa ZurloInterventional Radiology Unit, Miulli Hospital, Acquaviva Delle Fonti 70124, Italy.
Valentina FerraroUnit of Hepatobiliary Surgery, Miulli hospital, Acquaviva Delle Fonti 70124, Italy.
Riccardo MemeoUnit of Hepatobiliary Surgery, Miulli hospital, Acquaviva Delle Fonti 70124, Italy.
Stavros Spiliopoulos2 Radiology Department, National and Kapodistrian University of Athens, Chaidari Athens 12461, Greece.
Riccardo InchingoloInterventional Radiology Unit, Miulli Hospital, Acquaviva Delle Fonti 70124, Italy. riccardoin@hotmail.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous bilateral biliary stenting is an established method for the management of unresectable malignant hilar biliary obstruction.

aimTo evaluate the efficacy and safety of a novel uncovered biliary stent, specifically designed for hilar reconstruction.

methodsThis, single-center, retrospective study included 18 patients (mean age 71 ± 11 years; 61.1% male) undergoing percutaneous transhepatic Moving cell stent (MCS) placement for hilar reconstruction using the stent-in-stent technique for malignant biliary strictures, between November 2020 and July 2021. The Patients were diagnosed with cholangiocarcinoma (12/18; 66.6%), gallbladder cancer (5/18; 27.7%), and colorectal liver metastasis (1/18; 5.5%). Primary endpoints were technical (appropriate stent placement) and clinical (relief from jaundice) success. Secondary endpoints included stent patency, overall survival, complication rates and stent-related complications.

resultsThe technical and clinical success rates were 100% (18/18 cases). According to Kaplan-Meier analysis, the estimated overall patient survival was 80.5% and 60.4% at 6 and 12 mo respectively, while stent patency was 90.9% and 68.2% at 6 mo and 12 mo respectively. The mean stent patency was 172.53 ± 56.20 d and median stent patency was 165 d (range 83-315). Laboratory tests for cholestasis significantly improved after procedure: mean total bilirubin decreased from 15.2 ± 6.0 mg/dL to 1.3 ± 0.4 mg/dL (

conclusionPercutaneous hilar bifurcation biliary stenting with the MCS resulted in excellent clinical and technical success rates, with acceptable complication rates. Further studies are needed to confirm these initial positive results.

Indexed as

Bilateral Y-stentingHilar cholangiocarcinomaMalignant hilar biliary obstructionsPercutaneous approachSelf-expandable metallic stentStent-in-stent technique

Identifiers

PMID36187389
PMCPMC9516644

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