Evidence map›Paper›PMID 36187366›Full record

ArticleTherapeutic advances in gastroenterology2022

Intraductal fully covered self-expanding metal stents in the management of post-liver transplant anastomotic strictures: a UK wide experience.

Wafaa Ahmed, Dave Kyle, Amardeep Khanna, John Devlin, David Reffitt, Zeino Zeino, George Webster, Simon Phillpotts, Robert Gordon, Gareth Corbett and 16 more

Abstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Wafaa AhmedInstitute for Liver Studies, King's College Hospital NHS Foundation Trust, Denmark Hill, London SE5 9RS, UK.ORCID https://orcid.org/0000-0003-4034-7570
Dave KyleInstitute of Liver Studies, King's College Hospital NHS Foundation Trust, London, UK.
Amardeep KhannaInstitute of Liver Studies, King's College Hospital NHS Foundation Trust, London, UK.
John DevlinInstitute of Liver Studies, King's College Hospital NHS Foundation Trust, London, UK.
David ReffittInstitute of Liver Studies, King's College Hospital NHS Foundation Trust, London, UK.
Zeino ZeinoSouthmead Hospital/North Bristol NHS Trust, Bristol, UK.
George WebsterHepatopancreatobiliary Unit, University College Hospital, London, UK.
Simon PhillpottsHepatopancreatobiliary Unit, University College Hospital, London, UK.
Robert GordonCambridge Liver Unit, Addenbrooke's Hospital, Cambridge, UK.
Gareth CorbettCambridge Liver Unit, Addenbrooke's Hospital, Cambridge, UK.
William GelsonCambridge Liver Unit, Addenbrooke's Hospital, Cambridge, UK.
Manu NayarFreeman Hospital, Newcastle upon Tyne, UK.
Haider KhanSouthwest Liver Unit and Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK.
Matthew CrampSouthwest Liver Unit and Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK.
Jonathan PottsRoyal Free Sheila Sherlock Liver Centre, Royal Free Hospital and UCL Institute of Liver and Digestive Health, London, UK.
Waleed FateenRoyal Free Sheila Sherlock Liver Centre, Royal Free Hospital and UCL Institute of Liver and Digestive Health, London, UK.
Hamish MillerRoyal Free Sheila Sherlock Liver Centre, Royal Free Hospital and UCL Institute of Liver and Digestive Health, London, UK.
Bharat ParanandiLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Matthew HuggettLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Simon M EverettLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Vinod S HegadeLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Rebecca O'KaneBelfast Health and Social Care Trust, Belfast, UK.
Ryan ScottBelfast Health and Social Care Trust, Belfast, UK.
Neil McDougallBelfast Health and Social Care Trust, Belfast, UK.
Phillip HarrisonInstitute of Liver Studies, King's College Hospital NHS Foundation Trust, London, UK.
Deepak JoshiInstitute of Liver Studies, King's College Hospital NHS Foundation Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fully covered intraductal self-expanding metal stents (IDSEMS) have been well described in the management of post-liver transplant (LT) anastomotic strictures (ASs). Their antimigration waists and intraductal nature make them suited for deployment across the biliary anastomosis. Objectives: We conducted a multicentre study to analyse their use and efficacy in the management of AS. Design: This was a retrospective, multicentre observational study across nine tertiary centres in the United Kingdom. Methods: Consecutive patients who underwent endoscopic retrograde cholangiopancreatography with IDSEMS insertion were analysed retrospectively. Recorded variables included patient demographics, procedural characteristics, response to therapy and follow-up data. Results: In all, 162 patients (100 males, 62%) underwent 176 episodes of IDSEMS insertion for AS. Aetiology of liver disease in this cohort included hepatocellular carcinoma ( Conclusion: IDSEMS appears to be safe and highly efficacious in the management of post-LT AS, with low rates of AS recurrence.

Indexed as

biliary strictureERCPintra-ductal fully covered metal stentliver transplant

Identifiers

PMID36187366
PMCPMC9516418

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.