Evidence map›Paper›PMID 36187334›Full record

Trial reportOxidative medicine and cellular longevity2022

Antidyslipidemic, Antioxidant, and Anti-inflammatory Effects of Jelly Drink Containing Polyphenol-Rich Roselle Calyces Extract and Passion Fruit Juice with Pulp in Adults with Dyslipidemia: A Randomized, Double-Blind, Placebo-Controlled Trial.

Jurairat Khongrum, Pratoomporn Yingthongchai, Kongsak Boonyapranai, Wachira Wongtanasarasin, Nowwapan Donrung, Wanida Sukketsiri, Aree Prachansuwan, Pennapa Chonpathompikunlert

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Effects ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Potential of Fruits to Improve Dyslipidemias: A Pilot Review.Vascular health and risk management · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Effect of the Combination ofFoods (Basel, Switzerland) · 2023
    Review
  9. Therapeutic Potential ofPharmaceuticals (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jurairat KhongrumScience and Technology Research Institute, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID https://orcid.org/0000-0003-0347-2516
Pratoomporn YingthongchaiScience and Technology Research Institute, Chiang Mai University, Chiang Mai 50200, Thailand.
Kongsak BoonyapranaiResearch Institute for Health Science Chiang Mai University, Chiang Mai 50200, Thailand.ORCID https://orcid.org/0000-0003-1429-7709
Wachira WongtanasarasinDepartment of Emergency Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID https://orcid.org/0000-0002-1418-0036
Nowwapan DonrungExpert Center of Innovative Health Food and Biodiversity Research Centre, Thailand Institute of Scientific and Technological Research, 12120, Thailand.
Wanida SukketsiriDivision of Health and Applied Sciences, Faculty of Science, Prince of Songkla University, Songkhla 90110, Thailand.ORCID https://orcid.org/0000-0003-0836-1487
Aree PrachansuwanInstitute of Nutrition, Mahidol University, Nakhon Pathom 73170, Thailand.ORCID https://orcid.org/0000-0003-3062-276X
Pennapa ChonpathompikunlertExpert Center of Innovative Health Food and Biodiversity Research Centre, Thailand Institute of Scientific and Technological Research, 12120, Thailand.ORCID https://orcid.org/0000-0003-2764-0465

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress and inflammation play key roles in the pathophysiology in the pathophysiology of dyslipidemia, which are positive risks that increase atherosclerosis leading to important healthcare problems. Therefore, we aimed to study the antioxidant, anti-inflammatory, and lipid-lowering effects of jelly drink containing polyphenol-rich roselle calyces extract and passion fruit juice with pulp concentrate (RP jelly drink) in comparison to a placebo jelly drink for 8 weeks. Forty-three adults with dyslipidemia were randomly assigned into two groups: the RP jelly drink group and the placebo group. Glucose, total cholesterol (TC) triglyceride (TG), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), oxidative stress biomarkers, inflammatory parameters, and monocyte chemotactic protein-1 (MCP-1) were measured with fasting blood samples at baseline, 4 weeks and 8 weeks of intervention. Results showed a significant decrease in LDL-C and TG, respectively, after 8 weeks of RP jelly drink consumption (LDL-C: 107.63 ± 22.98

Indexed as

DyslipidemiasHibiscusAdultAnti-Inflammatory AgentsAntioxidantsBiomarkersChemokine CCL2Cholesterol, HDLCholesterol, LDLDouble-Blind MethodFruit and Vegetable JuicesGlucoseGlutathioneHumansInflammationInterleukin-10Anti-Inflammatory AgentsAntioxidantsBiomarkersChemokine CCL2Cholesterol, HDLCholesterol, LDLGlucoseGlutathioneInterleukin-10Interleukin-6MalondialdehydePlant ExtractsPolyphenolsTriglyceridesTumor Necrosis Factors

Identifiers

PMID36187334
PMCPMC9519340

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.