ArticleBiomedical optics express2022
Spatial resolution in optical coherence elastography of bounded media.
Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026Review
- Reconstruction of tensile and shear elastic moduli in anisotropic nearly incompressible media using Rayleigh wave phase and group velocities.Journal of biomedical optics · 2025Article
- Ultra-fast line-field swept source scanning optical coherence elastography.Biomedical optics express · 2025Article
- Wearable optical coherence tomography angiography probe with extended depth of field.Journal of biomedical optics · 2025Article
- Acoustomotive diffuse correlation spectroscopy for sensing mechanical stiffness in tissue-mimicking phantoms.Biomedical optics express · 2024Article
- In-vivo characterization of scleral rigidity in myopic eyes using fundus-pulsation optical coherence elastography.Biomedical optics express · 2024Article
- Wearable optical coherence tomography angiography probe for freely moving mice.Biomedical optics express · 2023Article
- Possible depth-resolved reconstruction of shear moduli in the cornea following collagen crosslinking (CXL) with optical coherence tomography and elastography.Biomedical optics express · 2023Article
- Article
- Acoustic Micro-Tapping Optical Coherence Elastography to Quantify Corneal Collagen Cross-Linking: An Ex Vivo Human Study.Ophthalmology science · 2023Article
- Noncontact Acoustic Micro-Tapping Optical Coherence Elastography for Quantification of Corneal Anisotropic Elasticity: In Vivo Rabbit Study.Translational vision science & technology · 2023Article
- Article
- Introduction to the Biophotonics Congress 2022 feature issue.Biomedical optics express · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Dynamic optical coherence elastography (OCE) tracks mechanical wave propagation in the subsurface region of tissue to image its shear modulus. For bulk shear waves, the lateral resolution of the reconstructed modulus map (i.e., elastographic resolution) can approach that of optical coherence tomography (OCT), typically a few tens of microns. Here we perform comprehensive numerical simulations and acoustic micro-tapping OCE experiments to show that for the typical situation of guided wave propagation in bounded media, such as cornea, the elastographic resolution cannot reach the OCT resolution and is mainly defined by the thickness of the bounded tissue layer. We considered the excitation of both broadband and quasi-harmonic guided waves in a bounded, isotropic medium. Leveraging the properties of broadband pulses, a robust method for modulus reconstruction with minimum artifacts at interfaces is demonstrated. In contrast, tissue bounding creates large instabilities in the phase of harmonic waves, leading to serious artifacts in modulus reconstructions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.