Evidence map›Paper›PMID 36187267›Full record

ArticleBiomedical optics express2022

En-face polarization-sensitive optical coherence tomography to characterize early-stage esophageal cancer and determine tumor margin.

Ping-Hsien Chen, Hiu-Ki Lai, Yi-Chen Yeh, Kuo-Wei Chang, Ming-Chih Hou, Wen-Chuan Kuo

Abstract read
In one paragraph

Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ping-Hsien ChenDepartment of Gastroenterology, West Garden Hospital, Taipei 108, Taiwan.
Hiu-Ki LaiInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Yi-Chen YehDepartment of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Kuo-Wei ChangInstitute of Oral Biology, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Ming-Chih HouDepartment of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Wen-Chuan KuoInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current imaging tools are insufficiently sensitive to the early diagnosis of esophageal squamous cell carcinoma (ESCC). The application of polarization-sensitive optical coherence tomography (PS-OCT) to detect tumor-stroma interaction is an interesting issue in cancer diagnosis. In this translational study, we found that en-face PS-OCT effectively characterizes protruding, flat, and depressive type ESCC regardless of animal or human specimens. In addition, the tumor contour and margin could also be drawn and determined on a broad en-face view. The determined tumor margin could be in the proximity of 2 mm to the actual tumor margin, which was proved directly using histology.

Identifiers

PMID36187267
PMCPMC9484435

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.