Evidence map›Paper›PMID 36187160›Full record

ArticleInternational journal of general medicine2022

Relationship Between Blood Eosinophils and Systemic Corticosteroid Therapy in COPD Exacerbation.

Yaya Gong, Hongyan Sun

Abstract read
In one paragraph

Article in International journal of general medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yaya GongDepartment of Respiratory Medicine, Anhui No.2 Provincial People's Hospital, Hefei, People's Republic of China.
Hongyan SunDepartment of Respiratory Medicine, Anhui No.2 Provincial People's Hospital, Hefei, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To assess the relationship between the duration of systemic corticosteroid therapy and blood eosinophil counts in patients with acute exacerbations of chronic obstructive pulmonary disease (COPD). Patients and Methods: This study included 292 patients with acute COPD exacerbations treated with daily intravenous injections of 40 mg/day methylprednisolone at the Department of Respiratory Medicine, Anhui No.2 Provincial People's Hospital, Hefei, China. The study subjects were divided into two groups - (1) a low-dose group (n = 136) that included patients treated with methylprednisolone for less than or equal to 5 days and (2) a high-dose group (n = 156) that included patients treated with methylprednisolone for more than 5 days. The blood eosinophil counts were analyzed for both the patient groups, and an optimal cut-off value was calculated to distinguish between the two groups. The study endpoints were readmission or deaths within 30 days or 180 days and re-infections within 90 days after hospital discharge. Results: The mean blood eosinophil counts in the low- and high-dose groups were 0.15 × 10 Conclusion: In patients with acute exacerbations of COPD, blood eosinophil counts of ≥0.115 × 10

Indexed as

chronic obstructive pulmonary diseasecorticosteroideosinophilsexacerbation

Identifiers

PMID36187160
PMCPMC9519011

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.