Evidence map›Paper›PMID 36187102›Full record

ArticleFrontiers in endocrinology2022

Case Report: Composite pheochromocytoma with ganglioneuroma component: A report of three cases.

Paula B Araujo, Mirna S Carvallo, Ana P Vidal, João B Nascimento, Julia M Wo, Erika O Naliato, Silvio H Cunha Neto, Flavia L Conceição, Rosita Fontes, Vinicius V de Lima and 5 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Paula B AraujoMedical Board of Clinical Analysis Department, Dasa, Rio de Janeiro, Brazil.
Mirna S CarvalloMedical School, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Ana P VidalPathology Service Clementino Fraga Filho University Hospital, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
João B NascimentoMedical School, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Julia M WoMedical School, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Erika O NaliatoRicardo Castilho Center of Studies Teresopolis Medical Association, Teresopolis, Rio de Janeiro, Brazil.
Silvio H Cunha NetoEndocrine Surgery Service, Hospital Universitario Clementino Fraga Filho, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Flavia L ConceiçãoMedical School, Endocrinology Unit, Hospital Universitario Clementino Fraga Filho, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Rosita FontesMedical Board of Clinical Analysis Department, Dasa, Rio de Janeiro, Brazil.
Vinicius V de LimaLaboratorio de Fisiologia Endocrina Doris Rosenthal, Instituto de Biofísica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Denise P CarvalhoLaboratorio de Fisiologia Endocrina Doris Rosenthal, Instituto de Biofísica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Paula SoaresInstitute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal.
Jorge LimaInstitute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal.
Delmar M LourençoEndocrine Genetic Unit, Endocrinology Division, Hospital das Clínicas, University of Sao Paulo School of Medicine, University of Sao Paulo, São Paulo, Brazil.
Alice Helena D ViolanteMedical School, Endocrinology Unit, Hospital Universitario Clementino Fraga Filho, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Universidade Federal do Rio de Janeiro · BRHospital Universitário Clementino Fraga Filho · BRi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto · PTCentro Universitário Serra dos Órgãos · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Composite pheochromocytoma (CP) is a very rare tumor originating from neural crest cells, predominantly composed of pheochromocytoma (PCC), a chromaffin cell tumor arising in adrenal medulla, and ganglioneuroma, a tumor derived from autonomic ganglion cells of the nervous system. Moreover, CP may be present in the hereditary syndromes of which pheochromocytoma is part. Literature offers scarce data on this subject, and particularly about its biological behavior, clinical evolution, and molecular profile. We report the phenotype and outcome of three cases of CP (PCC and ganglioneuroma components), followed up at the Endocrine Service of the Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, UFRJ, Rio de Janeiro, Brazil. Two nonsyndromic patients (cases 1 and 2) were negative to germline mutations in genes

Indexed as

Adrenal Gland NeoplasmsGanglioneuromaParagangliomaPheochromocytomaBrazilHumanscomposite pheocromocytomaganglioneuromamolecular studyparagangliomapathologypheocromocytoma

Identifiers

PMID36187102
PMCPMC9515550
OpenAlexW4297900532

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.