ArticleFrontiers in endocrinology2022
Maternal lipid profile during early pregnancy and birth weight: A retrospective study.
Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Global and regional incidence of intrahepatic cholestasis of pregnancy: a systematic review and meta-analysis.BMC medicine · 2025Pooled it
- Association of atherogenic index of plasma with gestational diabetes mellitus and birth weight outcomes, and the mediating role of blood glucose.Journal of diabetes investigation · 2026Article
- Genetic and maternal environmental contributions to estimated fetal weight at 20 weeks gestation compared with birthweight.medRxiv : the preprint server for health sciences · 2026Article
- Altered Lipid Profile and Oxidative Stress During Pregnancy: Impact on the Fetus and Risk of Metabolic Disorders in Adulthood.International journal of molecular sciences · 2026Review
- Relationship between maternal lipid profile during the third trimester and the risk of small-for-gestational-age birth: exploring inadequate gestational weight gain as a mediator.Lipids in health and disease · 2026Article
- Lipid profile analysis during pregnancy and its association with adverse pregnancy outcomes: a retrospective cohort study.BMC pregnancy and childbirth · 2026Article
- Advanced Maternal Age and Risk of Large-for-Gestational-Age Infants: Mediating Roles of Prenatal Body Mass Index and Specific Lipid Profiles.International journal of women's health · 2026Article
- Article
- The associations between maternal glycolipid metabolism and fetal growth in term births.Scientific reports · 2025Article
- Maternal dyslipidemia in the first trimester and adverse pregnancy and offspring outcomes: based on the Tianjin birth cohort.Lipids in health and disease · 2025Article
- Developing predictive models for full-term low birth weight infants using ten machine learning algorithms.BMC pediatrics · 2025Article
- Cardiometabolic Markers Associated With Altered Fetal Growth in Mediterranean Cohort.Maternal & child nutrition · 2025Article
- Early pregnancy maternal lipid profile, acute phase responders, and the association with preterm delivery and selected pregnancy outcomes.Pregnancy (Hoboken, N.J.) · 2025Article
- The mediating effect of maternal blood lipids on the association between maternal exposure to PMLipids in health and disease · 2025Article
- Saturation effects of pre-pregnancy BMI on infant birth weight in Jiangxi Province, China: a retrospective study.Scientific reports · 2025Article
- Physical activities and cardiometabolic profiles of African overweight and obese pregnant women.BMC pregnancy and childbirth · 2025Article
- Impact of maternal lipid profiles on offspring birth size in late pregnancy among women with and without gestational diabetes.Lipids in health and disease · 2025Article
- Article
- Article
- Evaluating the Impact of Maternal Lipid Profiles on Fetal Cardiac Function at Mid-Gestation: An Observational Study.Clinics and practice · 2024Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Elevated maternal serum lipid concentrations have been related to an adverse intrauterine environment and lead to abnormal birth weight. Objective: In this study, we aimed to explore the association between maternal lipid profiles during early pregnancy and birth weight with stratified pre-pregnancy body mass index (BMI). Methods: This retrospective cohort study was based on a large population from two major maternity centers in Shanghai, China. We included 57,516 women with singleton live birth between January 2018 and October 2020. All of the enrolled women had fasting lipid concentrations measured in early pregnancy. The primary outcomes were birth weight and risks of adverse birth outcomes, including macrosomia, large for gestational age (LGA), low birth weight (LBW), and small for gestational age (SGA). Results: Higher maternal concentrations of total cholesterol (TC), triglyceride (TG), and low-density cholesterol (LDL-c) in early pregnancy were associated with increased birth weight. Ln transformed TG and levels exhibited a positive association with LGA and macrosomia (OR = 1.33, 95% CI: 1.25, 1.42 and OR = 1.37, 95% CI: 1.24, 1.52) and showed a negative relationship with SGA (OR = 0.73, 95% CI: 0.62, 0.85). High TG (>75 Conclusions: Elevated maternal lipid profiles in early pregnancy are associated with higher birth weight and increased risks of LGA and macrosomia. We propose that serum lipid profiles in early pregnancy and pre-pregnancy BMI could serve as screening indexes for high-risk women.
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