Evidence map›Paper›PMID 36187092›Full record

ReviewFrontiers in endocrinology2022

Regulation of Pdx1 by oxidative stress and Nrf2 in pancreatic beta-cells.

Sharon Baumel-Alterzon, Donald K Scott

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 43 citations in OpenAlex.

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  17. Open veterinary journal · 2024
    Article
  18. Genetic and Epigenetic Factors in Gestational Diabetes Mellitus Pathology.International journal of molecular sciences · 2023
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Sharon Baumel-AlterzonDiabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Donald K ScottDiabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Child Health and Development Institute · USIcahn School of Medicine at Mount Sinai · US

Funding

Translational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STREAMSON C CHUA · 2015 to 2026
$27.7M
Alleviation of Glucotoxicity in Pancreatic Beta CellsR01DK130300 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SCOTT, DONALD K. · 2021 to 2024
$2.0M
Nrf2 and the adaptive expansion of beta cell massR01DK114338 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SCOTT, DONALD K. · 2018 to 2021
$1.7M
The role of Nrf2 in beta cell expansion during pregnancyK01DK128387 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ALTERZON, SHARON · 2022 to 2025
$550k
NIDDK NIH HHS K01 DK128387NIDDK NIH HHS P30 DK020541NIDDK NIH HHS R01 DK114338NIDDK NIH HHS R01 DK130300
6 · The paper itself

Abstract

The beta-cell identity gene, pancreatic duodenal homeobox 1 (

Indexed as

AntioxidantsNF-E2-Related Factor 2Oxidative StressPancreatic HormonesReactive Oxygen SpeciesAntioxidantsNF-E2-Related Factor 2Pancreatic HormonesReactive Oxygen Speciesbeta-cellsdiabetesNrf2oxidative-stressPdx1ROS

Identifiers

PMID36187092
PMCPMC9521308
OpenAlexW4296100578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.