Evidence map›Paper›PMID 36186990›Full record

ArticleFrontiers in cardiovascular medicine2022

Symptomatic intracerebral hemorrhage after non-emergency percutaneous coronary intervention: Incidence, risk factors, and association with cardiovascular outcomes.

Mervyn Jun Rui Lim, Yilong Zheng, Rodney Yu-Hang Soh, Qi Xuan Joel Foo, Andie Hartanto Djohan, Vincent Nga Diong Weng, Jamie Sin-Ying Ho, Tseng Tsai Yeo, Hui-Wen Sim, Tiong-Cheng Yeo and 4 more

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Role of Neuroimaging Before Coronary Angiography in Patients With Out-of-Hospital Cardiac Arrest.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mervyn Jun Rui LimDivision of Neurosurgery, National University Health System, Singapore, Singapore.
Yilong ZhengYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Rodney Yu-Hang SohDepartment of Cardiology, National University Heart Centre, Singapore, Singapore.
Qi Xuan Joel FooYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Andie Hartanto DjohanDepartment of Cardiology, National University Heart Centre, Singapore, Singapore.
Vincent Nga Diong WengDivision of Neurosurgery, National University Health System, Singapore, Singapore.
Jamie Sin-Ying HoAcademic Foundation Programme, North Middlesex University Hospital Trust, London, United Kingdom.
Tseng Tsai YeoDivision of Neurosurgery, National University Health System, Singapore, Singapore.
Hui-Wen SimDepartment of Cardiology, National University Heart Centre, Singapore, Singapore.
Tiong-Cheng YeoDepartment of Cardiology, National University Heart Centre, Singapore, Singapore.
Huay-Cheem TanDepartment of Cardiology, National University Heart Centre, Singapore, Singapore.
Mark Yan-Yee ChanDepartment of Cardiology, National University Heart Centre, Singapore, Singapore.
Joshua Ping-Yun LohDepartment of Cardiology, National University Heart Centre, Singapore, Singapore.
Ching-Hui SiaDepartment of Cardiology, National University Heart Centre, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the incidence, risk factors, and association with cardiovascular outcomes of patients who developed symptomatic intracerebral hemorrhage (ICH) after non-emergency percutaneous coronary intervention (PCI). Methods: We conducted a single-institution retrospective study of patients who developed symptomatic ICH after non-emergency PCI. To identify associations between clinical variables and outcomes, Cox-proportional hazards regression models were constructed. Outcomes analyzed include (1) all-cause mortality, (2) acute ischemic stroke (AIS) or transient ischemic attack (TIA), and (3) major adverse cardiovascular events (MACE). Results: A total of 1,732 patients were included in the analysis. The mean (±SD) age was 61.1 (±11.3) years, and 1,396 patients (80.6%) were male. The cumulative incidence of symptomatic ICH after non-emergency PCI was 1.3% (22 patients). Age, chronic kidney disease, and prior coronary artery bypass graft surgery were independently associated with a higher risk of ICH after PCI, while hyperlipidemia was independently associated with a lower risk of ICH after PCI. ICH after PCI was independently associated with a higher risk of all-cause mortality and AIS or TIA after PCI. Conclusion: Patients who are older, who have chronic kidney disease, and who have had prior coronary artery bypass graft surgery should be monitored for symptomatic ICH after non-emergency PCI.

Indexed as

cardiac catheterizationcerebrovascular diseaseepidemiologyhemorrhagic strokemyocardial infarction

Identifiers

PMID36186990
PMCPMC9524143

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.